Technology Process of cis-(3R,4R)-3,4-epoxytetradecanyl tosylate
There total 2 articles about cis-(3R,4R)-3,4-epoxytetradecanyl tosylate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium hydroxide;
In
diethyl ether;
at -5 ℃;
for 4h;
DOI:10.1021/jo9820871
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: l-Ipc2BOMe; LiN(c-Hex)2; BF3-OEt2 / tetrahydrofuran; diethyl ether / 4 h / -95 °C
1.2: H2O2; NaOH / tetrahydrofuran; H2O / 14 h / 20 °C
1.3: 67 percent / dicyclohexylborane / tetrahydrofuran / 4 h / 20 °C
2.1: 86 percent / KOH / diethyl ether / 4 h / -5 °C
With
(-)-B-methoxydiisopinocamphenylborane; potassium hydroxide; boron trifluoride diethyl etherate; lithium dicyclohexylamide;
In
tetrahydrofuran; diethyl ether;
1.1: Condensation / 1.2: Oxidation / 1.3: Addition / 2.1: Tosylation;
DOI:10.1021/jo9820871
- Guidance literature:
-
With
copper(l) iodide;
In
diethyl ether;
at -78 ℃;
for 0.5h;
DOI:10.1021/jo9820871
