C₂₅H₁₉F₆N₅O₂S₂

Base Information

Chemical Name:C₂₅H₁₉F₆N₅O₂S₂
CAS No.:1423161-12-9
Molecular Formula:C₂₅H₁₉F₆N₅O₂S₂
Molecular Weight:599.581
Hs Code.:

C<sub>25</sub>H<sub>19</sub>F<sub>6</sub>N<sub>5</sub>O<sub>2</sub>S<sub>2</sub>

Synonyms:C₂₅H₁₉F₆N₅O₂S₂

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Chemical Property of C₂₅H₁₉F₆N₅O₂S₂

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Technology Process of C₂₅H₁₉F₆N₅O₂S₂

There total 9 articles about C₂₅H₁₉F₆N₅O₂S₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.7%

: 925006-42-4
5-methyl-4-(trifluoromethyl)thiazol-2-amine

: 1423161-87-8
perfluorophenyl 1-methyl-3-(2-(1-methyl-1H-pyrazol-5-yl)-4-(trifluoromethyl)phenyl)-1H-indole-6-sulfonate

: 1423161-12-9
C₂₅H₁₉F₆N₅O₂S₂

Guidance literature:: With lithium hexamethyldisilazane; In tetrahydrofuran; Inert atmosphere; Cooling with ice;

Reference yield:

: 52415-29-9
6-bromo-1H-indole

: 1423161-12-9
C₂₅H₁₉F₆N₅O₂S₂

Guidance literature:: Multi-step reaction with 6 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.33 h / Inert atmosphere

1.2: 0.33 h / Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran / 0.5 h / Inert atmosphere; Cooling with acetone-dry ice

2.2: 0.58 h / 0 °C / Inert atmosphere; Cooling with acetone-dry ice

2.3: 0.25 h / 0 °C

3.1: N-Bromosuccinimide / dichloromethane / 2.5 h / Darkness

4.1: triethylamine / dichloromethane / 0.75 h

5.1: potassium phosphate; bis(di-tert-?butyl(4-?dimethylaminophenyl)?phosphine)?dichloropalladium(II) / 1,4-dioxane; water / 0.5 h / 90 °C / Inert atmosphere; Sealed tube; Microwave irradiation

6.1: lithium hexamethyldisilazane / tetrahydrofuran / Inert atmosphere; Cooling with ice

With potassium phosphate; N-Bromosuccinimide; n-butyllithium; bis(di-tert-?butyl(4-?dimethylaminophenyl)?phosphine)?dichloropalladium(II); sodium hydride; triethylamine; lithium hexamethyldisilazane; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; mineral oil; 5.1: |Suzuki Coupling;

Reference yield:

: 1041469-95-7
1-methyl-1H-indole-6-sulfonyl chloride

: 1423161-12-9
C₂₅H₁₉F₆N₅O₂S₂

Guidance literature:: Multi-step reaction with 4 steps

1: N-Bromosuccinimide / dichloromethane / 2.5 h / Darkness

2: triethylamine / dichloromethane / 0.75 h

3: potassium phosphate; bis(di-tert-?butyl(4-?dimethylaminophenyl)?phosphine)?dichloropalladium(II) / 1,4-dioxane; water / 0.5 h / 90 °C / Inert atmosphere; Sealed tube; Microwave irradiation

4: lithium hexamethyldisilazane / tetrahydrofuran / Inert atmosphere; Cooling with ice

With potassium phosphate; N-Bromosuccinimide; bis(di-tert-?butyl(4-?dimethylaminophenyl)?phosphine)?dichloropalladium(II); triethylamine; lithium hexamethyldisilazane; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; 3: |Suzuki Coupling;