3-iodopropylsulfonyl benzene

Base Information

• Chemical Name: 3-iodopropylsulfonyl benzene
• CAS No.: 141649-97-0
• Molecular Formula: C₉H₁₁IO₂S
• Molecular Weight: 310.156
• Mol file: 141649-97-0.mol

Synonyms:3-iodopropylsulfonyl benzene

Chemical Property of 3-iodopropylsulfonyl benzene

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 3-iodopropylsulfonyl benzene

There total 2 articles about 3-iodopropylsulfonyl benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

3-(phenylsulfonyl)propyl chloride (19432-96-3) → 3-iodopropylsulfonyl benzene (141649-97-0)

Guidance literature:

With sodium iodide; In acetone; for 12h; Heating;

DOI:10.1016/S0040-4020(01)88872-4

Reference yield:

3-chloropropyl phenyl sulfide (4911-65-3) → 3-iodopropylsulfonyl benzene (141649-97-0)

Guidance literature:

Multi-step reaction with 2 steps

1: dihydrogen peroxide / water / 5 h / 75 °C

2: sodium iodide / acetone / 18 h / Reflux

With dihydrogen peroxide; sodium iodide; In water; acetone;

DOI:10.1021/acs.joc.9b02112

Reference yield: 82.0%

3-iodopropylsulfonyl benzene (141649-97-0) + (1R,2S,3S,6R,7R,8R)-6-Isopropyl-3-methoxymethyl-10-oxo-12-oxa-tricyclo[6.3.1.02,7]dodecane-9-carboxylic acid methyl ester → (1R,2S,3S,6R,7R,8R,9S)-9-(3-Benzenesulfonyl-propyl)-6-isopropyl-3-methoxymethyl-10-oxo-12-oxa-tricyclo[6.3.1.02,7]dodecane-9-carboxylic acid methyl ester

Guidance literature:

With sodium hydride; In tetrahydrofuran; Heating;

DOI:10.1016/S0040-4039(01)02190-6

upstream raw materials:

3-(phenylsulfonyl)propyl chloride

3-chloropropyl phenyl sulfide

Downstream raw materials:

5-Carboethoxy-5-hexenyl phenyl sulfone