5-(4-chloro-phenyl)-thiophene-2-sulfonic acid (2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide

Base Information

Chemical Name:5-(4-chloro-phenyl)-thiophene-2-sulfonic acid (2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide
CAS No.:956125-98-7
Molecular Formula:C₂₀H₁₉ClN₂O₂S₂
Molecular Weight:418.968
Hs Code.:

5-(4-chloro-phenyl)-thiophene-2-sulfonic acid (2,3,4,5-tetrahydro-1<i>H</i>-benzo[<i>d</i>]azepin-7-yl)-amide

Synonyms:5-(4-chloro-phenyl)-thiophene-2-sulfonic acid (2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide

Suppliers and Price of 5-(4-chloro-phenyl)-thiophene-2-sulfonic acid (2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-(4-chloro-phenyl)-thiophene-2-sulfonic acid (2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-(4-chloro-phenyl)-thiophene-2-sulfonic acid (2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide

There total 3 articles about 5-(4-chloro-phenyl)-thiophene-2-sulfonic acid (2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 956125-86-3
7-[5-(4-chloro-phenyl)-thiophene-2-sulfonylamino]-1,2,4,5-tetrahydro-benzo[d]azepine-3-carboxylic acid tert-butyl ester

: 956125-98-7
5-(4-chloro-phenyl)-thiophene-2-sulfonic acid (2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide

Guidance literature:: With hydrogenchloride; In ethanol; at 20 ℃; for 2h;
DOI:10.1016/j.bmcl.2006.10.036

Reference yield:

: 209592-43-8
5-(4-chlorophenyl)thiophene-2-sulphonyl chloride

: 956125-98-7
5-(4-chloro-phenyl)-thiophene-2-sulfonic acid (2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / pyridine / CH₂Cl₂ / 12 h / 20 °C

2: 78 percent / HCl / ethanol / 2 h / 20 °C

With pyridine; hydrogenchloride; In ethanol; dichloromethane;
DOI:10.1016/j.bmcl.2006.10.036

Reference yield:

: 118454-24-3
7-amino-1,2,4,5-tetrahydro-benzo[d]azepine-3-carboxylic acid tert-butyl ester

: 956125-98-7
5-(4-chloro-phenyl)-thiophene-2-sulfonic acid (2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / pyridine / CH₂Cl₂ / 12 h / 20 °C

2: 78 percent / HCl / ethanol / 2 h / 20 °C

With pyridine; hydrogenchloride; In ethanol; dichloromethane;
DOI:10.1016/j.bmcl.2006.10.036