4(1H)-Pyrimidinone, tetrahydro-1-(2-(4-ethoxyphenyl)ethyl)-2-thioxo-

Base Information

Chemical Name:4(1H)-Pyrimidinone, tetrahydro-1-(2-(4-ethoxyphenyl)ethyl)-2-thioxo-
CAS No.:88655-28-1
Molecular Formula:C₁₄H₁₈N₂O₂S
Molecular Weight:278.375
Hs Code.:
DSSTox Substance ID:DTXSID30237226
Wikidata:Q83119328

Synonyms:BRN 5559437;4(1H)-Pyrimidinone, tetrahydro-1-(2-(4-ethoxyphenyl)ethyl)-2-thioxo-;Tetrahydro-1-(2-(4-ethoxyphenyl)ethyl)-2-thioxo-4(1H)-pyrimidinone;88655-28-1;DTXSID30237226;LS-136030

Suppliers and Price of 4(1H)-Pyrimidinone, tetrahydro-1-(2-(4-ethoxyphenyl)ethyl)-2-thioxo-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4(1H)-Pyrimidinone, tetrahydro-1-(2-(4-ethoxyphenyl)ethyl)-2-thioxo-

Chemical Property:

Density:1.23g/cm³
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:278.10889899
Heavy Atom Count:19
Complexity:327

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=CC=C(C=C1)CCN2CCC(=O)NC2=S

Technology Process of 4(1H)-Pyrimidinone, tetrahydro-1-(2-(4-ethoxyphenyl)ethyl)-2-thioxo-

There total 2 articles about 4(1H)-Pyrimidinone, tetrahydro-1-(2-(4-ethoxyphenyl)ethyl)-2-thioxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.8%

: ammonium thiocyanate

: 88655-08-7
3-[2-(4-Ethoxy-phenyl)-ethylamino]-propionic acid methyl ester

: 88655-28-1
1-[2-(4-Ethoxy-phenyl)-ethyl]-2-thioxo-tetrahydro-pyrimidin-4-one

Guidance literature:: In acetic acid; at 100 - 105 ℃; for 5h;
DOI:10.1007/BF00765024

Reference yield:

: 62885-82-9
2-(4-ethoxyphenyl)ethylamine

: 88655-28-1
1-[2-(4-Ethoxy-phenyl)-ethyl]-2-thioxo-tetrahydro-pyrimidin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 65.5 percent / methanol / 30 h / Ambient temperature

2: 24.8 percent / acetic acid / 5 h / 100 - 105 °C

In methanol; acetic acid;
DOI:10.1007/BF00765024