(2E,5S)-ethyl 5-(4-methoxyphenylamino)-5-(4-cyanophenyl)-pent-2-enoate

Base Information

• Chemical Name: (2E,5S)-ethyl 5-(4-methoxyphenylamino)-5-(4-cyanophenyl)-pent-2-enoate
• CAS No.: 1039451-65-4
• Molecular Formula: C₂₁H₂₂N₂O₃
• Molecular Weight: 350.417
• Mol file: 1039451-65-4.mol

Synonyms:(2E,5S)-ethyl 5-(4-methoxyphenylamino)-5-(4-cyanophenyl)-pent-2-enoate

Chemical Property of (2E,5S)-ethyl 5-(4-methoxyphenylamino)-5-(4-cyanophenyl)-pent-2-enoate

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of (2E,5S)-ethyl 5-(4-methoxyphenylamino)-5-(4-cyanophenyl)-pent-2-enoate

There total 1 articles about (2E,5S)-ethyl 5-(4-methoxyphenylamino)-5-(4-cyanophenyl)-pent-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(((4-methoxyphenyl)imino)methyl)benzonitrile (114046-25-2,20256-89-7) + tert-butyl((1-ethoxybuta-1,3-dien-1-yl)oxy)dimethylsilane (96995-10-7,96995-11-8,107174-27-6) → (2E,5S)-ethyl 5-(4-methoxyphenylamino)-5-(4-cyanophenyl)-pent-2-enoate (1039451-65-4) + (2E,5R)-ethyl 5-(4-methoxyphenylamino)-5-(4-cyanophenyl)-pent-2-enoate

Guidance literature:

With water; In tetrahydrofuran; tert-Amyl alcohol; tert-butyl alcohol; at -30 ℃; for 1h; Title compound not separated from byproducts.;

DOI:10.1002/anie.200800103

upstream raw materials:

4-(((4-methoxyphenyl)imino)methyl)benzonitrile

tert-butyl((1-ethoxybuta-1,3-dien-1-yl)oxy)dimethylsilane