2-amino-5-bromo-6-(3-fluorophenyl)-4(3H)pyrimidinone

Base Information

Chemical Name:2-amino-5-bromo-6-(3-fluorophenyl)-4(3H)pyrimidinone
CAS No.:74602-59-8
Molecular Formula:C₁₀H₇BrFN₃O
Molecular Weight:284.087
Hs Code.:
Mol file:74602-59-8.mol

Synonyms:4(1H)-Pyrimidinone,2-amino-5-bromo-6-(3-fluorophenyl)- (9CI);2-Amino-5-bromo-6-(3-fluorophenyl)-4(3H)-pyrimidinone; U 56499

Suppliers and Price of 2-amino-5-bromo-6-(3-fluorophenyl)-4(3H)pyrimidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-amino-5-bromo-6-(3-fluorophenyl)-4(3H)pyrimidinone

Chemical Property:

Vapor Pressure:2.04E-06mmHg at 25°C
Boiling Point:394°C at 760 mmHg
Flash Point:192.1°C
PSA：72.76000
Density:1.82g/cm³
LogP:2.26310

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-amino-5-bromo-6-(3-fluorophenyl)-4(3H)pyrimidinone

There total 2 articles about 2-amino-5-bromo-6-(3-fluorophenyl)-4(3H)pyrimidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 98305-63-6
2-Amino-6-(3-fluoro-phenyl)-3H-pyrimidin-4-one

: 74602-59-8
2-Amino-5-bromo-6-(3-fluoro-phenyl)-3H-pyrimidin-4-one

Guidance literature:: With bromine; In acetic acid; for 3h; Ambient temperature;
DOI:10.1021/jm00150a018

Reference yield:

: 33166-77-7
ethyl 3-(3-fluorophenyl)-3-oxopropanoate

: 74602-59-8
2-Amino-5-bromo-6-(3-fluoro-phenyl)-3H-pyrimidin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol; toluene / Heating

2: bromine / acetic acid / 3 h / Ambient temperature

With bromine; In ethanol; acetic acid; toluene;
DOI:10.1021/jm00150a018