5-Amino-3-ethyl-3-phenyl-2,6(1H,3H)-pyridinedione

Base Information

• Chemical Name: 5-Amino-3-ethyl-3-phenyl-2,6(1H,3H)-pyridinedione
• CAS No.: 14387-60-1
• Molecular Formula: C13H14 N2 O2
• Molecular Weight: 230.266
• Hs Code.: 2925190090
• Mol file: 14387-60-1.mol

Synonyms:Glutaconimide,2-amino-4-ethyl-4-phenyl- (8CI); 4-Amino-2-ethyl-2-phenylglutaconimide

Chemical Property of 5-Amino-3-ethyl-3-phenyl-2,6(1H,3H)-pyridinedione

Chemical Property:

• Vapor Pressure: 4.55E-08mmHg at 25°C
• Melting Point: 161-162 °C(Solv: ethanol (64-17-5))
• Boiling Point: 443.7°C at 760 mmHg
• PKA: 8.62±0.60(Predicted)
• Flash Point: 222.1°C
• PSA: 75.68000
• Density: 1.183g/cm³
• LogP: 1.80960

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Amino-3-ethyl-3-phenyl-2,6(1H,3H)-pyridinedione

There total 1 articles about 5-Amino-3-ethyl-3-phenyl-2,6(1H,3H)-pyridinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 5-amino-3-ethyl-3-phenyl-3H-pyridine-2,6-dione (14387-60-1)

Guidance literature:

DOI:10.1021/jm00241a019

Reference yield: 78.0%

phthalic anhydride (85-44-9) + 5-amino-3-ethyl-3-phenyl-3H-pyridine-2,6-dione (14387-60-1) → N-(5-ethyl-2,6-dioxo-5-phenyl-1,2,5,6-tetrahydro-pyridin-3-yl)-phthalimide (14980-60-0)

Guidance literature:

In acetic acid; for 6h; Heating;

DOI:10.1002/(SICI)1521-4184(199801)331:1<7::AID-ARDP7>3.0.CO;2-N

Reference yield: 67.0%

3,4-dimethoxyphthalic anhydride (1567-56-2) + 5-amino-3-ethyl-3-phenyl-3H-pyridine-2,6-dione (14387-60-1) → 2-(5-ethyl-5-phenyl-2,6-dioxo-1,2,5,6-tetrahydropyridin-3-yl)-4,5-dimethoxy-1,3-dihydro-2H-isoindole-1,3-dione

Guidance literature:

In acetic acid; Heating;

DOI:10.1002/(SICI)1521-4184(199801)331:1<7::AID-ARDP7>3.0.CO;2-N

Downstream raw materials:

N-(5-ethyl-2,6-dioxo-5-phenyl-1,2,5,6-tetrahydro-pyridin-3-yl)-phthalimide

5-amino-3-ethyl-3-phenyl-piperidine-2,6-dione