α-<4-Chlor-phenoxy>-4-chlor-propiophenon

Base Information

• Chemical Name: α-<4-Chlor-phenoxy>-4-chlor-propiophenon
• CAS No.: 74228-88-9
• Molecular Formula: C₁₅H₁₂Cl₂O₂
• Molecular Weight: 295.165
• Mol file: 74228-88-9.mol

Synonyms:α-<4-Chlor-phenoxy>-4-chlor-propiophenon

Chemical Property of α-<4-Chlor-phenoxy>-4-chlor-propiophenon

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α-<4-Chlor-phenoxy>-4-chlor-propiophenon

There total 2 articles about α-<4-Chlor-phenoxy>-4-chlor-propiophenon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.5%

2-bromo-1-(4-chlorophenyl)-1-propanone (877-37-2) + 4-chloro-phenol (106-48-9,82344-39-6) → α-<4-Chlor-phenoxy>-4-chlor-propiophenon (74228-88-9)

Guidance literature:

With potassium carbonate; In acetone; for 5h; Heating;

DOI:10.1007/BF00777381

Reference yield:

→ α-<4-Chlor-phenoxy>-4-chlor-propiophenon (74228-88-9)

Guidance literature:

aus α-Brom-4-chlor-propiophenon beim Erwaermen mit 4-Chlor-phenol u. K2CO3 in Acn.;

DOI:10.1021/jo01081a010

Reference yield: 85.5%

α-<4-Chlor-phenoxy>-4-chlor-propiophenon (74228-88-9) → 5-Chloro-3-(4-chloro-phenyl)-2-methyl-benzofuran (74228-93-6)

Guidance literature:

With phosphoric acid; phosphorus pentoxide; at 60 ℃; for 3.5h;

DOI:10.1007/BF00777381

upstream raw materials:

2-bromo-1-(4-chlorophenyl)-1-propanone

4-chloro-phenol

Downstream raw materials:

5-Chloro-3-(4-chloro-phenyl)-2-methyl-benzofuran