1-[(4-phenylpiperidin-4-yl)carbonyl]piperidine monohydrochloride

Base Information

Chemical Name:1-[(4-phenylpiperidin-4-yl)carbonyl]piperidine monohydrochloride
CAS No.:83863-47-2
Molecular Formula:C₁₇H₂₄N₂O*ClH
Molecular Weight:308.851
Hs Code.:
Mol file:83863-47-2.mol

Synonyms:1-[(4-phenylpiperidin-4-yl)carbonyl]piperidine monohydrochloride

Suppliers and Price of 1-[(4-phenylpiperidin-4-yl)carbonyl]piperidine monohydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 6 raw suppliers

Chemical Property of 1-[(4-phenylpiperidin-4-yl)carbonyl]piperidine monohydrochloride

Chemical Property:

Vapor Pressure:2.44E-08mmHg at 25°C
Boiling Point:451.4°C at 760 mmHg
Flash Point:199.2°C
PSA：23.55000
LogP:3.72040

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-[(4-phenylpiperidin-4-yl)carbonyl]piperidine monohydrochloride

There total 4 articles about 1-[(4-phenylpiperidin-4-yl)carbonyl]piperidine monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 846060-68-2
4-phenyl-4-(piperidine-1-carbonyl)piperidine-1-carboxylic acid tert-butyl ester

: 83863-47-2
(4-Phenyl-piperidin-4-yl)-piperidin-1-yl-methanone; hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane;
DOI:10.1016/S0960-894X(97)10013-0

Reference yield:

: 110-89-4
piperidine

: 83863-47-2
(4-Phenyl-piperidin-4-yl)-piperidin-1-yl-methanone; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: EDC, HOBt, DIEA / CH₂Cl₂

2: 4N HCl / dioxane

With hydrogenchloride; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; dichloromethane;
DOI:10.1016/S0960-894X(97)10013-0

Reference yield:

: 167262-68-2
N-(t-butyloxycarbonyl)-4-phenylpiperidine-4-carboxylic acid

: 83863-47-2
(4-Phenyl-piperidin-4-yl)-piperidin-1-yl-methanone; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: EDC, HOBt, DIEA / CH₂Cl₂

2: 4N HCl / dioxane

With hydrogenchloride; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; dichloromethane;
DOI:10.1016/S0960-894X(97)10013-0