dibenzyl [3-(4-{(2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-4-oxo-1-[4-(pyrimidin-2-ylethynyl)phenyl]azetidin-2-yl}phenyl)prop-2-yn-1-yl]malonate

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Chemical Name:dibenzyl [3-(4-{(2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-4-oxo-1-[4-(pyrimidin-2-ylethynyl)phenyl]azetidin-2-yl}phenyl)prop-2-yn-1-yl]malonate
CAS No.:1227268-02-1
Molecular Formula:C₅₂H₄₂FN₃O₇
Molecular Weight:839.92
Hs Code.:

dibenzyl [3-(4-{(2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-4-oxo-1-[4-(pyrimidin-2-ylethynyl)phenyl]azetidin-2-yl}phenyl)prop-2-yn-1-yl]malonate

Synonyms:dibenzyl [3-(4-{(2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-4-oxo-1-[4-(pyrimidin-2-ylethynyl)phenyl]azetidin-2-yl}phenyl)prop-2-yn-1-yl]malonate

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Chemical Property of dibenzyl [3-(4-{(2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-4-oxo-1-[4-(pyrimidin-2-ylethynyl)phenyl]azetidin-2-yl}phenyl)prop-2-yn-1-yl]malonate

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Technology Process of dibenzyl [3-(4-{(2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-4-oxo-1-[4-(pyrimidin-2-ylethynyl)phenyl]azetidin-2-yl}phenyl)prop-2-yn-1-yl]malonate

There total 1 articles about dibenzyl [3-(4-{(2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-4-oxo-1-[4-(pyrimidin-2-ylethynyl)phenyl]azetidin-2-yl}phenyl)prop-2-yn-1-yl]malonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1227267-94-8
dibenzyl (3-{4-[(2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-1-(4-ethynylphenyl)-4-oxoazetidin-2-yl]phenyl}prop-2-yn-1-yl)malonate

: 4595-60-2
2-bromopyrimidine

: 1227268-02-1
dibenzyl [3-(4-{(2S,3R)-3-[(3S)-3-(acetyloxy)-3-(4-fluorophenyl)propyl]-4-oxo-1-[4-(pyrimidin-2-ylethynyl)phenyl]azetidin-2-yl}phenyl)prop-2-yn-1-yl]malonate

Guidance literature:: With copper(l) iodide; tetra-(n-butyl)ammonium iodide; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl-formamide; at 70 ℃; for 16h; Inert atmosphere; Sealed tube;