3'-O-<(tert-butyl)dimethylsilyl>-5'-deoxy-N6-<2-(4-nitrophenyl)ethoxycarbonyl>-5'-<<2-(4-nitrophenyl)ethoxycarbonyl>amino>adenosine

Base Information

Chemical Name:3'-O-<(tert-butyl)dimethylsilyl>-5'-deoxy-N6-<2-(4-nitrophenyl)ethoxycarbonyl>-5'-<<2-(4-nitrophenyl)ethoxycarbonyl>amino>adenosine
CAS No.:173097-79-5
Molecular Formula:C₃₄H₄₂N₈O₁₁Si
Molecular Weight:766.84
Hs Code.:

Synonyms:3'-O-<(tert-butyl)dimethylsilyl>-5'-deoxy-N6-<2-(4-nitrophenyl)ethoxycarbonyl>-5'-<<2-(4-nitrophenyl)ethoxycarbonyl>amino>adenosine

Suppliers and Price of 3'-O-<(tert-butyl)dimethylsilyl>-5'-deoxy-N6-<2-(4-nitrophenyl)ethoxycarbonyl>-5'-<<2-(4-nitrophenyl)ethoxycarbonyl>amino>adenosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3'-O-<(tert-butyl)dimethylsilyl>-5'-deoxy-N6-<2-(4-nitrophenyl)ethoxycarbonyl>-5'-<<2-(4-nitrophenyl)ethoxycarbonyl>amino>adenosine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3'-O-<(tert-butyl)dimethylsilyl>-5'-deoxy-N6-<2-(4-nitrophenyl)ethoxycarbonyl>-5'-<<2-(4-nitrophenyl)ethoxycarbonyl>amino>adenosine

There total 5 articles about 3'-O-<(tert-butyl)dimethylsilyl>-5'-deoxy-N6-<2-(4-nitrophenyl)ethoxycarbonyl>-5'-<<2-(4-nitrophenyl)ethoxycarbonyl>amino>adenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 21950-36-7
5'-amino-5'-deoxy-2',3'-O-isopropylideneadenosine

: 173097-79-5
3'-O-<(tert-butyl)dimethylsilyl>-5'-deoxy-N6-<2-(4-nitrophenyl)ethoxycarbonyl>-5'-<<2-(4-nitrophenyl)ethoxycarbonyl>amino>adenosine

Guidance literature:: Multi-step reaction with 3 steps

1: 75 percent / CH₂Cl₂ / 18 h / Ambient temperature

2: 76 percent / 80 percent formic acid / H₂O / 5 h / Ambient temperature

3: 31 percent / 1H-imidazole / pyridine / 18 h / Ambient temperature

With 1H-imidazole; formic acid; In pyridine; dichloromethane; water;
DOI:10.1002/hlca.19950780711

Reference yield:

: 362-75-4
2',3'-isopropylidene adenosine

: 173097-79-5
3'-O-<(tert-butyl)dimethylsilyl>-5'-deoxy-N6-<2-(4-nitrophenyl)ethoxycarbonyl>-5'-<<2-(4-nitrophenyl)ethoxycarbonyl>amino>adenosine

Guidance literature:: Multi-step reaction with 6 steps

1: NaHCO₃ / H₂O; pyridine / 18 h / Ambient temperature

2: NaN₃ / dimethylformamide / 0.67 h / 65 - 68 °C

3: conc. NH₄OH, PPh₃ / pyridine / 18 h / Ambient temperature

4: 75 percent / CH₂Cl₂ / 18 h / Ambient temperature

5: 76 percent / 80 percent formic acid / H₂O / 5 h / Ambient temperature

6: 31 percent / 1H-imidazole / pyridine / 18 h / Ambient temperature

With 1H-imidazole; ammonium hydroxide; formic acid; sodium azide; sodium hydrogencarbonate; triphenylphosphine; In pyridine; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1002/hlca.19950780711

Reference yield:

: 34245-48-2
5'-azido-5'-deoxy-2',3'-O-isopropylidene adenosine

: 173097-79-5
3'-O-<(tert-butyl)dimethylsilyl>-5'-deoxy-N6-<2-(4-nitrophenyl)ethoxycarbonyl>-5'-<<2-(4-nitrophenyl)ethoxycarbonyl>amino>adenosine

Guidance literature:: Multi-step reaction with 4 steps

1: conc. NH₄OH, PPh₃ / pyridine / 18 h / Ambient temperature

2: 75 percent / CH₂Cl₂ / 18 h / Ambient temperature

3: 76 percent / 80 percent formic acid / H₂O / 5 h / Ambient temperature

4: 31 percent / 1H-imidazole / pyridine / 18 h / Ambient temperature

With 1H-imidazole; ammonium hydroxide; formic acid; triphenylphosphine; In pyridine; dichloromethane; water;
DOI:10.1002/hlca.19950780711