tert-butyl 4-(1-(2-(trifluoromethyl)phenylsulfonyl)-1H-indazol-3-yl)benzoate

Base Information

Chemical Name:tert-butyl 4-(1-(2-(trifluoromethyl)phenylsulfonyl)-1H-indazol-3-yl)benzoate
CAS No.:1392809-11-8
Molecular Formula:C₂₅H₂₁F₃N₂O₄S
Molecular Weight:502.514
Hs Code.:

Synonyms:tert-butyl 4-(1-(2-(trifluoromethyl)phenylsulfonyl)-1H-indazol-3-yl)benzoate

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Chemical Property of tert-butyl 4-(1-(2-(trifluoromethyl)phenylsulfonyl)-1H-indazol-3-yl)benzoate

Chemical Property:

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Technology Process of tert-butyl 4-(1-(2-(trifluoromethyl)phenylsulfonyl)-1H-indazol-3-yl)benzoate

There total 4 articles about tert-butyl 4-(1-(2-(trifluoromethyl)phenylsulfonyl)-1H-indazol-3-yl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1392808-94-4
tert-butyl 4-(1H-indazol-3-yl)benzoate

: 776-04-5
2-trifluoromethylbenzenesulfonyl chloride

: 1392809-11-8
tert-butyl 4-(1-(2-(trifluoromethyl)phenylsulfonyl)-1H-indazol-3-yl)benzoate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃;

Reference yield:

: 850568-54-6
(4-(tert-butoxycarbonyl)phenyl)boronic acid

: 1392809-11-8
tert-butyl 4-(1-(2-(trifluoromethyl)phenylsulfonyl)-1H-indazol-3-yl)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane; water / 100 °C / Inert atmosphere

2: triethylamine / dichloromethane / 20 °C

With sodium carbonate; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; dichloromethane; water; 1: Suzuki-Miyaura reaction;

Reference yield:

: 1257296-40-4
tert-butyl 3-bromo-1H-indazole-1-carboxylate

: 1392809-11-8
tert-butyl 4-(1-(2-(trifluoromethyl)phenylsulfonyl)-1H-indazol-3-yl)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane; water / 100 °C / Inert atmosphere

2: triethylamine / dichloromethane / 20 °C

With sodium carbonate; triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; dichloromethane; water; 1: Suzuki-Miyaura reaction;