1-O-(2-amino-2-deoxy-α-D-glucopyranosyl)-D-myo-inositol hydrochloride

Base Information

• Chemical Name: 1-O-(2-amino-2-deoxy-α-D-glucopyranosyl)-D-myo-inositol hydrochloride
• CAS No.: 1228173-30-5
• Molecular Formula: C₁₂H₂₃NO₁₀*ClH
• Molecular Weight: 377.776
• Mol file: 1228173-30-5.mol

Synonyms:1-O-(2-amino-2-deoxy-α-D-glucopyranosyl)-D-myo-inositol hydrochloride

Chemical Property of 1-O-(2-amino-2-deoxy-α-D-glucopyranosyl)-D-myo-inositol hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-O-(2-amino-2-deoxy-α-D-glucopyranosyl)-D-myo-inositol hydrochloride

There total 2 articles about 1-O-(2-amino-2-deoxy-α-D-glucopyranosyl)-D-myo-inositol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

C47H53NO10 (1228173-28-1) → 1-O-(2-amino-2-deoxy-α-D-glucopyranosyl)-D-myo-inositol hydrochloride (1228173-30-5)

Guidance literature:

With hydrogenchloride; 20 % Pd(OH)2/C; hydrogen; In water; tert-butyl alcohol; for 6h;

DOI:10.1021/ol1008334

Reference yield: 98.0%

1-O-[2-azido-3-O-(4-bromobenzyl)-2-deoxy-4-O-(2-naphthylmethyl)-α-D-glucopyranosyl]-2,4,5,6-tetra-O-benzyl-D-myo-inositol (1334379-58-6) → 1-O-(2-amino-2-deoxy-α-D-glucopyranosyl)-D-myo-inositol hydrochloride (1228173-30-5)

Guidance literature:

With hydrogenchloride; hydrogen; palladium(II) hydroxide; In methanol; water; for 72h;

DOI:10.1021/ol202218n

Reference yield: 78.0%

1-O-(2-amino-2-deoxy-α-D-glucopyranosyl)-D-myo-inositol hydrochloride (1228173-30-5) + N-(tert-butoxycarbonyl)-S-acetyl-L-cysteine (21948-02-7) → 1-O-[2-deoxy-2-(N-tert-butyloxycarbonyl-S-acetyl-L-cysteinyl)amino-α-D-glucopyranosyl]-D-myo-inositol (1228173-37-2)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 4 - 20 ℃; Inert atmosphere;

DOI:10.1021/ol202218n

upstream raw materials:

C₄₇H₅₃NO₁₀

1-O-[2-azido-3-O-(4-bromobenzyl)-2-deoxy-4-O-(2-naphthylmethyl)-α-D-glucopyranosyl]-2,4,5,6-tetra-O-benzyl-D-myo-inositol

Downstream raw materials:

1-O-[2-deoxy-2-(N-tert-butyloxycarbonyl-S-acetyl-L-cysteinyl)amino-α-D-glucopyranosyl]-D-myo-inositol

1-O-(2'-[N-acetyl-L-cysteinyl]amido-2'-deoxy-α-D-glucopyranosyl)-D-myo-inositol