Technology Process of C18H17(2)H3O
There total 8 articles about C18H17(2)H3O which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
n-butyllithium;
In
tetrahydrofuran;
at -50 ℃;
for 1h;
DOI:10.1021/ja00293a039
- Guidance literature:
-
Multi-step reaction with 5 steps
1: Mg / 1.) Et2O, 2.) reflux, 0.5 h
2: 50.9 g / formic acid / 26 h
3: 78 percent / 1.) NaNH2 / diethyl ether; liquid ammonia / 1.) from -45 degC to 0 degC over 3 h; 2., room t, 3 h
4: m-chloroperbenzoic acid / CH2Cl2 / 0.5 h / -70 °C
5: n-BuLi / tetrahydrofuran / 1 h / -50 °C
With
n-butyllithium; formic acid; sodium amide; magnesium; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; diethyl ether; dichloromethane; ammonia;
DOI:10.1021/ja00293a039
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1.) SOCl2, pyridine; 2.) LiEt3BD / 1.) benzene, reflux, 0.5 h; 2.) THF, room t., 24 h
2: Mg / 1.) Et2O, 2.) reflux, 0.5 h
3: 50.9 g / formic acid / 26 h
4: 78 percent / 1.) NaNH2 / diethyl ether; liquid ammonia / 1.) from -45 degC to 0 degC over 3 h; 2., room t, 3 h
5: m-chloroperbenzoic acid / CH2Cl2 / 0.5 h / -70 °C
6: n-BuLi / tetrahydrofuran / 1 h / -50 °C
With
pyridine; lithium triethyl borodeuteride; n-butyllithium; formic acid; thionyl chloride; sodium amide; magnesium; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; diethyl ether; dichloromethane; ammonia;
DOI:10.1021/ja00293a039
