Histamine hydrochloride

Base Information

Chemical Name:Histamine hydrochloride
CAS No.:55-36-7
Molecular Formula:C5H10ClN3
Molecular Weight:147.608
Hs Code.:
NSC Number:757057,257873
UNII:F9I23AC4PQ
DSSTox Substance ID:DTXSID70946542
Wikidata:Q27277851
ChEMBL ID:CHEMBL535166

Synonyms:Ceplene;Histamine;Histamine Dihydrochloride;Histamine Hydrochloride;Peremin

Suppliers and Price of Histamine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 12 raw suppliers

Chemical Property of Histamine hydrochloride

Chemical Property:

Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:147.0563250
Heavy Atom Count:9
Complexity:64.7

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(NC=N1)CCN.Cl

Technology Process of Histamine hydrochloride

There total 3 articles about Histamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 51-45-6
histamine

: 55-36-7,56-92-8,23758-34-1,78654-37-2
histamine dihydrochloride

Guidance literature:: With hydrogenchloride; In ethanol; for 1h; Reflux; Industrial scale;

Reference yield: 85.1%

: 71-00-1,26062-48-6,90081-11-1
L-histidine

: 55-36-7,56-92-8,23758-34-1,78654-37-2
histamine dihydrochloride

Guidance literature:: L-histidine; With para-methylacetophenone; In dimethyl sulfoxide; N,N-dimethyl-formamide; at 140 ℃; for 4h; Inert atmosphere;

With hydrogenchloride; In water; at 25 ℃; for 0.5h; pH=5 - 6; Reagent/catalyst; Solvent; Temperature; Cooling;

Reference yield: 80.0%

: 71-00-1
L-histidine

: 55-36-7,56-92-8,23758-34-1,78654-37-2
histamine dihydrochloride

Guidance literature:: L-histidine; With acetophenone; In 1-methyl-pyrrolidin-2-one; at 200 - 210 ℃; Inert atmosphere;

With hydrogenchloride; In dichloromethane; isopropyl alcohol; pH=1 - 2;