2-(4-(hydroxylamino)phenyl)-1,1-dicyanoethylene

Base Information

• Chemical Name: 2-(4-(hydroxylamino)phenyl)-1,1-dicyanoethylene
• CAS No.: 234435-71-3
• Molecular Formula: C₁₀H₇N₃O
• Molecular Weight: 185.185
• Mol file: 234435-71-3.mol

Synonyms:2-(4-(hydroxylamino)phenyl)-1,1-dicyanoethylene

Chemical Property of 2-(4-(hydroxylamino)phenyl)-1,1-dicyanoethylene

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2-(4-(hydroxylamino)phenyl)-1,1-dicyanoethylene

There total 1 articles about 2-(4-(hydroxylamino)phenyl)-1,1-dicyanoethylene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

4-Nitrobenzylidenemalononitrile (2700-23-4) → 2-(4-(hydroxylamino)phenyl)-1,1-dicyanoethylene (234435-71-3)

Guidance literature:

With sodium hypophosphite; palladium on activated charcoal; In tetrahydrofuran; water; at 40 - 45 ℃; for 2h;

DOI:10.1021/jo990235x

Reference yield: 82.0%

2-(4-(hydroxylamino)phenyl)-1,1-dicyanoethylene (234435-71-3) → 2-(4-nitrosophenyl)-1,1-dicyanoethylene (234435-72-4)

Guidance literature:

With tert-butylhypochlorite; In tetrahydrofuran; at -78 - -20 ℃;

DOI:10.1021/jo990235x

Reference yield:

2-(4-(hydroxylamino)phenyl)-1,1-dicyanoethylene (234435-71-3) → 2-(4-((4-methoxyphenyl)diazenyl)phenyl)-1,1-dicyanoethylene

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / t-BuOCl / tetrahydrofuran / -78 - -20 °C

2: 70 percent / glacial AcOH / Ambient temperature

With tert-butylhypochlorite; acetic acid; In tetrahydrofuran;

DOI:10.1021/jo990235x

upstream raw materials:

4-Nitrobenzylidenemalononitrile

Downstream raw materials:

2-(4-nitrosophenyl)-1,1-dicyanoethylene