3-{2-[3-(4-amino-phenyl)-3-oxo-propionylamino]-thiazol-4-yl}-benzenesulfonyl fluoride

Base Information

Chemical Name:3-{2-[3-(4-amino-phenyl)-3-oxo-propionylamino]-thiazol-4-yl}-benzenesulfonyl fluoride
CAS No.:2865-12-5
Molecular Formula:C₁₈H₁₄FN₃O₄S₂
Molecular Weight:419.457
Hs Code.:

Synonyms:3-{2-[3-(4-amino-phenyl)-3-oxo-propionylamino]-thiazol-4-yl}-benzenesulfonyl fluoride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-{2-[3-(4-amino-phenyl)-3-oxo-propionylamino]-thiazol-4-yl}-benzenesulfonyl fluoride

Chemical Property:

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Technology Process of 3-{2-[3-(4-amino-phenyl)-3-oxo-propionylamino]-thiazol-4-yl}-benzenesulfonyl fluoride

There total 4 articles about 3-{2-[3-(4-amino-phenyl)-3-oxo-propionylamino]-thiazol-4-yl}-benzenesulfonyl fluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2182-21-0
3-{2-[3-(4-nitro-phenyl)-3-oxo-propionylamino]-thiazol-4-yl}-benzenesulfonyl fluoride

: 2865-12-5
3-{2-[3-(4-amino-phenyl)-3-oxo-propionylamino]-thiazol-4-yl}-benzenesulfonyl fluoride

Guidance literature:: With hydrogen; nickel; In 1,4-dioxane; at 80 ℃; under 77572.2 Torr;
DOI:10.1021/jo01016a038

Reference yield:

: 2196-70-5
3-(2-amino-thiazol-4-yl)-benzenesulfonyl fluoride

: 2865-12-5
3-{2-[3-(4-amino-phenyl)-3-oxo-propionylamino]-thiazol-4-yl}-benzenesulfonyl fluoride

Guidance literature:: Multi-step reaction with 2 steps

2: H₂ / Raney-Ni / dioxane / 80 °C / 77572.2 Torr

With hydrogen; nickel; In 1,4-dioxane;
DOI:10.1021/jo01016a038

Reference yield:

: 838-57-3
ethyl 4-nitrobenzoylacetate

: 2865-12-5
3-{2-[3-(4-amino-phenyl)-3-oxo-propionylamino]-thiazol-4-yl}-benzenesulfonyl fluoride

Guidance literature:: Multi-step reaction with 2 steps

2: H₂ / Raney-Ni / dioxane / 80 °C / 77572.2 Torr

With hydrogen; nickel; In 1,4-dioxane;
DOI:10.1021/jo01016a038