2-<<2-<(5-Amino-1,2,4-oxadiazol-3-yl)amino>ethoxy>methyl>-4-(2,3-dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridine

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Chemical Name:2-<<2-<(5-Amino-1,2,4-oxadiazol-3-yl)amino>ethoxy>methyl>-4-(2,3-dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridine
CAS No.:118070-86-3
Molecular Formula:C₂₂H₂₅Cl₂N₅O₆
Molecular Weight:526.376
Hs Code.:

Synonyms:2-<<2-<(5-Amino-1,2,4-oxadiazol-3-yl)amino>ethoxy>methyl>-4-(2,3-dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridine

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Chemical Property of 2-<<2-<(5-Amino-1,2,4-oxadiazol-3-yl)amino>ethoxy>methyl>-4-(2,3-dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridine

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Technology Process of 2-<<2-<(5-Amino-1,2,4-oxadiazol-3-yl)amino>ethoxy>methyl>-4-(2,3-dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridine

There total 2 articles about 2-<<2-<(5-Amino-1,2,4-oxadiazol-3-yl)amino>ethoxy>methyl>-4-(2,3-dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

: 93117-89-6
N-<2-<<4-(2,3-Dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridin-2-yl>methoxy>ethyl>-N'-cyano-S-methylisothiourea

: 118070-86-3
2-<<2-<(5-Amino-1,2,4-oxadiazol-3-yl)amino>ethoxy>methyl>-4-(2,3-dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridine

Guidance literature:: With hydroxylamine hydrochloride; triethylamine; In ethanol; for 4h; Heating;
DOI:10.1021/jm00123a009

Reference yield:

: 88150-50-9
2-[(2-aminoethoxy)methyl]-4-(2,3-dichlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine

: 118070-86-3
2-<<2-<(5-Amino-1,2,4-oxadiazol-3-yl)amino>ethoxy>methyl>-4-(2,3-dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridine

Guidance literature:: Multi-step reaction with 2 steps

1: propan-2-ol / Ambient temperature

2: 22 percent / NH₂OH*HCl, triethylamine / ethanol / 4 h / Heating

With hydroxylamine hydrochloride; triethylamine; In ethanol; isopropyl alcohol;
DOI:10.1021/jm00123a009