2,4(1H,3H)-Pyrimidinedione, 1-[(2-hydroxyethoxy)methyl]-5-(1-methyleth yl)-6-(phenylseleno)-

Base Information

Chemical Name:2,4(1H,3H)-Pyrimidinedione, 1-[(2-hydroxyethoxy)methyl]-5-(1-methyleth yl)-6-(phenylseleno)-
CAS No.:172255-86-6
Molecular Formula:C₁₆H₂₀N₂O₄Se
Molecular Weight:383.306
Hs Code.:
Mol file:172255-86-6.mol

Synonyms:2,4(1H,3H)-Pyrimidinedione, 1-[(2-hydroxyethoxy)methyl]-5-(1-methyleth yl)-6-(phenylseleno)-

Suppliers and Price of 2,4(1H,3H)-Pyrimidinedione, 1-[(2-hydroxyethoxy)methyl]-5-(1-methyleth yl)-6-(phenylseleno)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 2,4(1H,3H)-Pyrimidinedione, 1-[(2-hydroxyethoxy)methyl]-5-(1-methyleth yl)-6-(phenylseleno)-

Chemical Property:

PSA：84.58000
LogP:-0.30630

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2,4(1H,3H)-Pyrimidinedione, 1-[(2-hydroxyethoxy)methyl]-5-(1-methyleth yl)-6-(phenylseleno)-

There total 4 articles about 2,4(1H,3H)-Pyrimidinedione, 1-[(2-hydroxyethoxy)methyl]-5-(1-methyleth yl)-6-(phenylseleno)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 172256-34-7
1-[[2-(tert-butyldimethylsiloxy)ethoxy]methyl]-5-isopropyluracil

: 172255-86-6
1-[(2-hydroxyethoxy)methyl]-5-isopropyl-6-(phenylselenenyl)-uracil

Guidance literature:

Reference yield:

: 1026536-28-6
1-[2-(tert-Butyl-dimethyl-silanyloxy)-ethoxymethyl]-5-isopropyl-6-phenylselanyl-1H-pyrimidine-2,4-dione

: 172255-86-6
1-[(2-hydroxyethoxy)methyl]-5-isopropyl-6-(phenylselenenyl)-uracil

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; for 2h; Yield given; Ambient temperature;
DOI:10.1002/jhet.5570330446

Reference yield:

: 17432-95-0
5-isopropyluracil

: 172255-86-6
1-[(2-hydroxyethoxy)methyl]-5-isopropyl-6-(phenylselenenyl)-uracil

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) N,O-bis(trimethylsilyl)acetamide / 1.) dichloromethane, 2 h, RT, 2.) dichloromethane, cyclohexane, 3 h, RT

2: imidazole / dimethylformamide / 16 h / Ambient temperature

3: 1.) lithium bis(trimethylsilyl)amide / 1.) THF, -70 deg C, 1 h, 2.) THF, a) -70 deg C, b) RT, 16 h

4: conc. aq. HCl / tetrahydrofuran / 2 h / Ambient temperature

With 1H-imidazole; hydrogenchloride; N,O-bis-(trimethylsilyl)-acetamide; lithium hexamethyldisilazane; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1002/jhet.5570330446