Technology Process of (Z)-7-((4-methoxybenzyl)oxy)-5-methylhept-5-enal
There total 4 articles about (Z)-7-((4-methoxybenzyl)oxy)-5-methylhept-5-enal which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione;
In
dichloromethane; dimethyl sulfoxide;
at 0 - 20 ℃;
for 4h;
DOI:10.1021/jo301287z
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: diisobutylaluminium hydride / toluene; dichloromethane / 0.5 h / -78 °C / Inert atmosphere
2.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C
2.2: 3 h / 0 - 20 °C
3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C
4.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / dichloromethane; dimethyl sulfoxide / 4 h / 0 - 20 °C
With
tetrabutyl ammonium fluoride; sodium hydride; diisobutylaluminium hydride; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione;
In
tetrahydrofuran; dichloromethane; dimethyl sulfoxide; toluene;
DOI:10.1021/jo301287z
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C
1.2: 3 h / 0 - 20 °C
2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 20 °C
3.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / dichloromethane; dimethyl sulfoxide / 4 h / 0 - 20 °C
With
tetrabutyl ammonium fluoride; sodium hydride; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione;
In
tetrahydrofuran; dichloromethane; dimethyl sulfoxide;
DOI:10.1021/jo301287z
