1-bromo-3,3-dimethylcyclohexene

Base Information

• Chemical Name: 1-bromo-3,3-dimethylcyclohexene
• CAS No.: 182187-66-2
• Molecular Formula: C₈H₁₃Br
• Molecular Weight: 189.095
• Mol file: 182187-66-2.mol

Synonyms:1-bromo-3,3-dimethylcyclohexene

Chemical Property of 1-bromo-3,3-dimethylcyclohexene

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1-bromo-3,3-dimethylcyclohexene

There total 2 articles about 1-bromo-3,3-dimethylcyclohexene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

6-bromo-2,2-dimethylcyclohexanol → 1-bromo-3,3-dimethylcyclohexene (182187-66-2)

Guidance literature:

With pyridine; dmap; trifluoromethylsulfonic anhydride; In dichloromethane;

DOI:10.1016/S0040-4039(96)01482-7

Reference yield:

6-bromo-2,2-dimethylcyclohexan-1-one (21690-26-6) → 1-bromo-3,3-dimethylcyclohexene (182187-66-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / NaBH₄

2: 60 percent / triflic anhydride, pyridine, DMAP / CH₂Cl₂

With pyridine; dmap; sodium tetrahydroborate; trifluoromethylsulfonic anhydride; In dichloromethane;

DOI:10.1016/S0040-4039(96)01482-7

Reference yield: 62.0%

1-bromo-3,3-dimethylcyclohexene (182187-66-2) + N1,N4-dimethoxy-N1,N4-dimethylsuccinamide (243988-27-4) → 1,4-bis(3,3-dimethylcyclohexen-1-yl)butane-1,4-dione

Guidance literature:

1-bromo-3,3-dimethylcyclohexene; With iodine; magnesium; ethylene dibromide; lithium chloride; In tetrahydrofuran; at 40 - 80 ℃; Inert atmosphere; Schlenk technique;

N¹,N⁴-dimethoxy-N¹,N⁴-dimethylsuccinamide; In tetrahydrofuran; diethyl ether; at 23 ℃; Inert atmosphere; Schlenk technique; Cooling;

DOI:10.1002/ejoc.201901043

upstream raw materials:

6-bromo-2,2-dimethylcyclohexan-1-one