(E)-9-methoxy-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)vinyl)pyrazolo[1,5-c]quinazoline

Base Information

Chemical Name:(E)-9-methoxy-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)vinyl)pyrazolo[1,5-c]quinazoline
CAS No.:1263193-53-8
Molecular Formula:C₂₄H₂₁N₅O
Molecular Weight:395.464
Hs Code.:

Synonyms:(E)-9-methoxy-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)vinyl)pyrazolo[1,5-c]quinazoline

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Chemical Property of (E)-9-methoxy-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)vinyl)pyrazolo[1,5-c]quinazoline

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Technology Process of (E)-9-methoxy-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)vinyl)pyrazolo[1,5-c]quinazoline

There total 1 articles about (E)-9-methoxy-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)vinyl)pyrazolo[1,5-c]quinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 123511-51-3
1-methyl-4-phenyl-1H-imidazole-2-carbaldehyde

: 1263193-44-7
C₃₁H₂₇N₃OP⁽¹⁺⁾*Cl^(1-)

: 1263193-53-8
(E)-9-methoxy-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)vinyl)pyrazolo[1,5-c]quinazoline

Guidance literature:: C₃₁H₂₇N₃OP⁽¹⁺⁾*Cl^(1-); With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at -5 ℃; for 0.5h;

1-methyl-4-phenyl-1H-imidazole-2-carbaldehyde; In N,N-dimethyl-formamide; mineral oil; at -5 - 20 ℃; for 1.5h;
DOI:10.1016/j.bmc.2010.10.038

Reference yield: 71.0%

: 1263193-53-8
(E)-9-methoxy-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)vinyl)pyrazolo[1,5-c]quinazoline

: 1263193-16-3
9-methoxy-2-methyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)ethyl)pyrazolo[1,5-c]quinazoline

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; at 20 ℃; for 6h; under 2327.23 Torr;
DOI:10.1016/j.bmc.2010.10.038