Pyrido(3,4-d)pyridazine-1,4-dione, 8-amino-5-chloro-2,3-dihydro-7-phenyl-

Base Information

• Chemical Name: Pyrido(3,4-d)pyridazine-1,4-dione, 8-amino-5-chloro-2,3-dihydro-7-phenyl-
• CAS No.: 143323-55-1
• Molecular Formula: C13H9 Cl N4 O2
• Molecular Weight: 288.693
• DSSTox Substance ID: DTXSID30162387
• Nikkaji Number: J1.565.936J
• Wikidata: Q83031051
• Mol file: 143323-55-1.mol

Synonyms:8-amino-5-chloro-7-phenylpyrido(3,4-d)pyridazine-1,4(2H,3H)dione;L 012;L-012

Chemical Property of Pyrido(3,4-d)pyridazine-1,4-dione, 8-amino-5-chloro-2,3-dihydro-7-phenyl-

Chemical Property:

• PKA: 8.15±0.20(Predicted)
• PSA: 105.15000
• Density: 1.487g/cm³
• LogP: 2.91980
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 288.0414032
• Heavy Atom Count: 20
• Complexity: 413

Purity/Quality:

99% ^*data from raw suppliers

L 012 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=C(C3=C(C(=O)NNC3=O)C(=N2)Cl)N

Technology Process of Pyrido(3,4-d)pyridazine-1,4-dione, 8-amino-5-chloro-2,3-dihydro-7-phenyl-

There total 1 articles about Pyrido(3,4-d)pyridazine-1,4-dione, 8-amino-5-chloro-2,3-dihydro-7-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-amino-6-chloro-4,5-diethoxycarbonyl-2-phenylpyridine (143323-41-5) → 8-amino-5-chloro-2,3-dihydro-7-phenylpyrido[3,4-d]pyridazine-1,4-dione (143323-55-1)

Guidance literature:

With hydrazine hydrate; In nitrogen; water;

Reference yield:

8-amino-5-chloro-2,3-dihydro-7-phenylpyrido[3,4-d]pyridazine-1,4-dione (143323-55-1) → C13H9(18)FN4O2

Guidance literature:

With [¹⁸F]-potassium fluoride; [2.2.2]cryptande; In N,N-dimethyl-formamide;

upstream raw materials:

3-amino-6-chloro-4,5-diethoxycarbonyl-2-phenylpyridine

Refernces