(S)-1-[3,5-bis(trifluoromethyl)benzyl]-5-[(2-methoxymethylpyrrolidin-1-yl)sulfonyl]isatin

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Chemical Name:(S)-1-[3,5-bis(trifluoromethyl)benzyl]-5-[(2-methoxymethylpyrrolidin-1-yl)sulfonyl]isatin
CAS No.:1146968-92-4
Molecular Formula:C₂₃H₂₀F₆N₂O₅S
Molecular Weight:550.479
Hs Code.:

Synonyms:(S)-1-[3,5-bis(trifluoromethyl)benzyl]-5-[(2-methoxymethylpyrrolidin-1-yl)sulfonyl]isatin

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Chemical Property of (S)-1-[3,5-bis(trifluoromethyl)benzyl]-5-[(2-methoxymethylpyrrolidin-1-yl)sulfonyl]isatin

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Technology Process of (S)-1-[3,5-bis(trifluoromethyl)benzyl]-5-[(2-methoxymethylpyrrolidin-1-yl)sulfonyl]isatin

There total 1 articles about (S)-1-[3,5-bis(trifluoromethyl)benzyl]-5-[(2-methoxymethylpyrrolidin-1-yl)sulfonyl]isatin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 32247-96-4
3,5-bis(trifluoromethyl)benzyl bromide

: 220509-74-0,1110670-49-9
(S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin

: 1146968-92-4
(S)-1-[3,5-bis(trifluoromethyl)benzyl]-5-[(2-methoxymethylpyrrolidin-1-yl)sulfonyl]isatin

Guidance literature:: (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 0.5h; Inert atmosphere;

3,5-bis(trifluoromethyl)benzyl bromide; In N,N-dimethyl-formamide; mineral oil; at 20 ℃;
DOI:10.1016/j.bmc.2009.02.048