((3Z)-7-methoxycarbonyl-3-heptenyl)-triphenylphosphonium iodide

Base Information

• Chemical Name: ((3Z)-7-methoxycarbonyl-3-heptenyl)-triphenylphosphonium iodide
• CAS No.: 91097-63-1
• Molecular Formula: C₂₇H₃₀O₂P*I
• Molecular Weight: 544.412
• Mol file: 91097-63-1.mol

Synonyms:((3Z)-7-methoxycarbonyl-3-heptenyl)-triphenylphosphonium iodide

Chemical Property of ((3Z)-7-methoxycarbonyl-3-heptenyl)-triphenylphosphonium iodide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ((3Z)-7-methoxycarbonyl-3-heptenyl)-triphenylphosphonium iodide

There total 8 articles about ((3Z)-7-methoxycarbonyl-3-heptenyl)-triphenylphosphonium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

methyl (5Z)-8-iodooct-5-enoate (91173-04-5) + triphenylphosphine (603-35-0) → ((3Z)-7-methoxycarbonyl-3-heptenyl)-triphenylphosphonium iodide (91097-63-1)

Guidance literature:

In acetonitrile; Heating;

DOI:10.1016/S0040-4039(00)73109-1

Reference yield:

(Z)-8-hydroxyoct-5-enoic acid methyl ester (83606-22-8) → ((3Z)-7-methoxycarbonyl-3-heptenyl)-triphenylphosphonium iodide (91097-63-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 99 percent / CBr₄; dppe / CH₂Cl₂ / 0.75 h / 20 °C

2: 99 percent / NaI / acetone / 3 h / Heating

3: 76 percent / acetonitrile / 19 h / Heating

With carbon tetrabromide; 1,2-bis-(diphenylphosphino)ethane; sodium iodide; In dichloromethane; acetone; acetonitrile; 1: Substitution / 2: Substitution / 3: Addition;

DOI:10.1021/ol006430b

Reference yield:

methyl 4-formylbutanoate (6026-86-4) → ((3Z)-7-methoxycarbonyl-3-heptenyl)-triphenylphosphonium iodide (91097-63-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 86 percent / tetrahydrofuran / 2 h / -78 - 0 °C

2: 99 percent / CBr₄; dppe / CH₂Cl₂ / 0.75 h / 20 °C

3: 99 percent / NaI / acetone / 3 h / Heating

4: 76 percent / acetonitrile / 19 h / Heating

With carbon tetrabromide; 1,2-bis-(diphenylphosphino)ethane; sodium iodide; In tetrahydrofuran; dichloromethane; acetone; acetonitrile; 1: Addition / 2: Substitution / 3: Substitution / 4: Addition;

DOI:10.1021/ol006430b

upstream raw materials:

methyl (5Z)-8-iodooct-5-enoate

triphenylphosphine

methyl 4-formylbutanoate

1-methoxycyclopentene

Downstream raw materials:

Benzoic acid (2E,4E,7Z)-(S)-11-methoxycarbonyl-1-pentyl-undeca-2,4,7-trienyl ester

Benzoic acid (2E,4Z,7Z)-(R)-11-methoxycarbonyl-1-pentyl-undeca-2,4,7-trienyl ester

12-oxo-5Z,8Z,10E,14Z-eicosatetraenoic acid

(R)-12-HETE