(R)-tert-butyl 4-(5-bromothiazol-2-yl)-1-(4-(trifluoromethyl)phenyl)butan-2-ylcarbamate

Base Information

Chemical Name:(R)-tert-butyl 4-(5-bromothiazol-2-yl)-1-(4-(trifluoromethyl)phenyl)butan-2-ylcarbamate
CAS No.:1236031-48-3
Molecular Formula:C₁₉H₂₂BrF₃N₂O₂S
Molecular Weight:479.361
Hs Code.:

Synonyms:(R)-tert-butyl 4-(5-bromothiazol-2-yl)-1-(4-(trifluoromethyl)phenyl)butan-2-ylcarbamate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-tert-butyl 4-(5-bromothiazol-2-yl)-1-(4-(trifluoromethyl)phenyl)butan-2-ylcarbamate

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Technology Process of (R)-tert-butyl 4-(5-bromothiazol-2-yl)-1-(4-(trifluoromethyl)phenyl)butan-2-ylcarbamate

There total 1 articles about (R)-tert-butyl 4-(5-bromothiazol-2-yl)-1-(4-(trifluoromethyl)phenyl)butan-2-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1236031-47-2
(R)-tert-butyl 4-(thiazol-2-yl)-1-(4-(trifluoromethyl)phenyl)butan-2-ylcarbamate

: 1236031-48-3
(R)-tert-butyl 4-(5-bromothiazol-2-yl)-1-(4-(trifluoromethyl)phenyl)butan-2-ylcarbamate

Guidance literature:: With N-Bromosuccinimide; In N,N-dimethyl-formamide; at 20 ℃; for 22h;

Reference yield: 41.0%

: 1105710-34-6
3-fluoroisoquinolin-6-ylboronic acid

: 1236031-48-3
(R)-tert-butyl 4-(5-bromothiazol-2-yl)-1-(4-(trifluoromethyl)phenyl)butan-2-ylcarbamate

: 1236031-49-4
tert-butyl (R)-4-(5-(3-fluoroisoquinolin-6-yl)thiazol-2-yl)-1-(4-(trifluoromethyl)phenyl)butan-2-ylcarbamate

Guidance literature:: With potassium acetate; bis[di-t-butyl(p-dimethylaminophenyl)phosphino]palladium (II) Dichloride; In water; acetonitrile; at 80 ℃; for 3h;