Technology Process of C24H29NO4
There total 5 articles about C24H29NO4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
Hoveyda-Grubbs catalyst second generation;
In
dichloromethane;
at 20 ℃;
for 1h;
optical yield given as %de;
stereoselective reaction;
Inert atmosphere;
DOI:10.1021/ol201704g
- Guidance literature:
-
Multi-step reaction with 4 steps
1: tetrahydrofuran; toluene / 3.5 h / -78 °C / Inert atmosphere
2: hydrogenchloride; water / methanol / 2 h
3: potassium carbonate / water; acetone; toluene / 1 h / 20 °C
4: Hoveyda-Grubbs catalyst second generation / dichloromethane / 1 h / 20 °C / Inert atmosphere
With
hydrogenchloride; Hoveyda-Grubbs catalyst second generation; water; potassium carbonate;
In
tetrahydrofuran; methanol; dichloromethane; water; acetone; toluene;
1: Grignard addition;
DOI:10.1021/ol201704g
- Guidance literature:
-
Multi-step reaction with 4 steps
1: tetrahydrofuran; toluene / 3.5 h / -78 °C / Inert atmosphere
2: hydrogenchloride; water / methanol / 2 h
3: potassium carbonate / water; acetone; toluene / 1 h / 20 °C
4: Hoveyda-Grubbs catalyst second generation / dichloromethane / 1 h / 20 °C / Inert atmosphere
With
hydrogenchloride; Hoveyda-Grubbs catalyst second generation; water; potassium carbonate;
In
tetrahydrofuran; methanol; dichloromethane; water; acetone; toluene;
1: Grignard addition;
DOI:10.1021/ol201704g