(4-benzenesulfonyl-5-ethoxy-2,3-dihydro-furan-2-ylmethyl)-tert-butyl-diphenyl-silane

Base Information

• Chemical Name: (4-benzenesulfonyl-5-ethoxy-2,3-dihydro-furan-2-ylmethyl)-tert-butyl-diphenyl-silane
• CAS No.: 362610-86-4
• Molecular Formula: C₂₉H₃₄O₄SSi
• Molecular Weight: 506.738
• Mol file: 362610-86-4.mol

Synonyms:(4-benzenesulfonyl-5-ethoxy-2,3-dihydro-furan-2-ylmethyl)-tert-butyl-diphenyl-silane

Chemical Property of (4-benzenesulfonyl-5-ethoxy-2,3-dihydro-furan-2-ylmethyl)-tert-butyl-diphenyl-silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4-benzenesulfonyl-5-ethoxy-2,3-dihydro-furan-2-ylmethyl)-tert-butyl-diphenyl-silane

There total 2 articles about (4-benzenesulfonyl-5-ethoxy-2,3-dihydro-furan-2-ylmethyl)-tert-butyl-diphenyl-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

1-benzenesulfonyl-2-[(tert-butyl-diphenyl-silanyl)-methyl]-cyclopropanecarboxylic acid ethyl ester (362610-82-0) → (4-benzenesulfonyl-5-ethoxy-2,3-dihydro-furan-2-ylmethyl)-tert-butyl-diphenyl-silane (362610-86-4)

Guidance literature:

With titanium tetrachloride; In dichloromethane; at -30 - 20 ℃; for 8h;

DOI:10.1021/ol0163169

Reference yield:

3-(tert-butyldiphenylsilyl)propene (138566-91-3) → (4-benzenesulfonyl-5-ethoxy-2,3-dihydro-furan-2-ylmethyl)-tert-butyl-diphenyl-silane (362610-86-4)

Guidance literature:

Multi-step reaction with 2 steps

1: Rh

2: 75 percent / TiCl₄ / CH₂Cl₂ / 8 h / -30 - 20 °C

With titanium tetrachloride; rhodium; In dichloromethane;

DOI:10.1021/ol0163169

Reference yield:

(4-benzenesulfonyl-5-ethoxy-2,3-dihydro-furan-2-ylmethyl)-tert-butyl-diphenyl-silane (362610-86-4) → 5-[(tert-butyl-diphenyl-silanyl)-methyl]-dihydro-furan-2-one

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / HClO₄ / tetrahydrofuran; H₂O / 5 h / Heating

2: 74 percent / Na₂HPO₄; sodium amalgum / methanol / 4 h

With disodium hydrogenphosphate; sodium amalgam; perchloric acid; In tetrahydrofuran; methanol; water;

DOI:10.1021/ol0163169

upstream raw materials:

1-benzenesulfonyl-2-[(tert-butyl-diphenyl-silanyl)-methyl]-cyclopropanecarboxylic acid ethyl ester

3-(tert-butyldiphenylsilyl)propene