2'-O-methyl-5'-O-(monomethoxytrityl)-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine 3'-<2-(4-nitrophenyl)ethyl isopropyl(methyl)phosphoramidite>

Base Information

• Chemical Name: 2'-O-methyl-5'-O-(monomethoxytrityl)-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine 3'-<2-(4-nitrophenyl)ethyl isopropyl(methyl)phosphoramidite>
• CAS No.: 226882-11-7
• Molecular Formula: C₅₂H₅₅N₈O₁₂P
• Molecular Weight: 1015.03

Synonyms:2'-O-methyl-5'-O-(monomethoxytrityl)-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine 3'-<2-(4-nitrophenyl)ethyl isopropyl(methyl)phosphoramidite>

Chemical Property of 2'-O-methyl-5'-O-(monomethoxytrityl)-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine 3'-<2-(4-nitrophenyl)ethyl isopropyl(methyl)phosphoramidite>

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Technology Process of 2'-O-methyl-5'-O-(monomethoxytrityl)-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine 3'-<2-(4-nitrophenyl)ethyl isopropyl(methyl)phosphoramidite>

There total 1 articles about 2'-O-methyl-5'-O-(monomethoxytrityl)-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine 3'-<2-(4-nitrophenyl)ethyl isopropyl(methyl)phosphoramidite> which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2'-O-methyl-5'-O-(monomethoxytrityl)-N6-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine (185761-09-5) + 2-(4-nitrophenyl)ethyl isopropyl(methyl)phosphoramidochloridite (226881-84-1) → 2'-O-methyl-5'-O-(monomethoxytrityl)-N6-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine 3'-<2-(4-nitrophenyl)ethyl isopropyl(methyl)phosphoramidite> (226882-11-7)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; Ambient temperature;

DOI:10.1002/(SICI)1522-2675(19990407)82:4<614::AID-HLCA614>3.0.CO;2-Y

upstream raw materials:

2'-O-methyl-5'-O-(monomethoxytrityl)-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine

2-(4-nitrophenyl)ethyl isopropyl(methyl)phosphoramidochloridite

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