Mpomeovt

Base Information

• Chemical Name: Mpomeovt
• CAS No.: 77327-45-8
• Molecular Formula: C₄₈H₇₄N₁₂O₁₂S₂
• Molecular Weight: 1075.32
• Mol file: 77327-45-8.mol

Synonyms:(d(CH2)5,Tyr(Me)2,Orn8)vasotocin;1-(beta-mercapto-(beta,beta-cyclopentamethylene)propionic acid)-2-tyr(OMe)-8-Orn-oxytocin;1-deamino-2-O-methyl-tyrosyl-8-ornithine-1-(beta-mercapto-(beta,beta-cyclopentamethylene)propionic acid)oxytocin;d(CH2)5Tyr(Me)-8-Orn-vasotocin;dET2Tyr(Me)-OVT;MPOMeOVT;oxytocin, 1-(beta-mercapto-(beta, beta-cyclopentamethylene)propionic acid)-O-methyltyrosyl(2)-ornithine(8)-;oxytocin, 1-(beta-mercapto-(beta,beta-cyclopentamethylene)propionic acid)-1-deamino-2-O-methyl-tyrosyl-8-ornithine-;oxytocin, 1beta-Mpa(beta-(CH2)5)(1)-Me(Tyr)(2)-Orn(8)-;oxytocin,1-(beta-mercapto-(beta, beta-cyclopentamethylene)propionic acid)-Tyr(OMe)(2)-Orn(8)-;vasotocin, 1-(beta-mercapto-(beta, beta-cyclopentamethylene)propionic acid)-Tyr(OM3)(2)-Orn(8)-;vasotocin, d(CH2)5-2-O-methytyrosine-8-ornithine-

Chemical Property of Mpomeovt

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.625
• Boiling Point: 1537.6 °C at 760 mmHg
• Flash Point: 883.7 °C
• Density: 1.36 g/cm³
• Storage Temp.: −20°C
• XLogP3: -1.7
• Hydrogen Bond Donor Count: 11
• Hydrogen Bond Acceptor Count: 15
• Rotatable Bond Count: 19
• Exact Mass: 1074.49905819
• Heavy Atom Count: 74
• Complexity: 2010

Purity/Quality:

99% ^*data from raw suppliers

[β-Mercapto-β,β-cyclopentamethylenepropionyl1, O-Me-Tyr2, Orn8]-Oxytocin ≥93% (HPLC), solid ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(CSSC2(CCCCC2)CC(=O)NC(C(=O)N1)CC3=CC=C(C=C3)OC)C(=O)N4CCCC4C(=O)NC(CCCN)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N
• Isomeric SMILES: CC[C@H](C)C1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC2(CCCCC2)CC(=O)N[C@H](C(=O)N1)CC3=CC=C(C=C3)OC)C(=O)N4CCC[C@H]4C(=O)N[C@@H](CCCN)C(=O)NCC(=O)N)CC(=O)N)CCC(=O)N
• Uses: [β-Mercapto-β,β-cyclopentamethylenepropionyl1, O-Me-Tyr2, Orn8]-Oxytocin has been used as an oxytocin receptor antagonist:to study the influence of blockading the oxytocin receptors in the anterior cingulate cortex on helping behavior to determine the receptors that mediate vasopressin-stimulated anion secretion across cultured porcine vas deferens epithelial cell monolayers to study the influence of oxytocin receptors inhibition on intravenous and in situ oxytocin effects on the urinary bladder and cardiovascular activities in sham rats

Technology Process of Mpomeovt

There total 1 articles about Mpomeovt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

d(CH2)5-Tyr(Me)-Ile-Gln-Asn-D-Cys-Pro-Orn-Gly-NH2 → d(CH2)5[Tyr(Me)2,D-Cys6]OVT (77327-45-8)

Guidance literature:

With acetic acid; potassium hexacyanoferrate(III); for 0.333333h; Yield given;

DOI:10.1021/jm00010a020

Refernces