Benzyl-2-azido-3,4-di-O-<α,α-D2>benzyl-2-desoxy-β-D-glucopyranosid

Base Information

• Chemical Name: Benzyl-2-azido-3,4-di-O-<α,α-D2>benzyl-2-desoxy-β-D-glucopyranosid
• CAS No.: 106115-82-6
• Molecular Formula: C₂₇H₂₉N₃O₅
• Molecular Weight: 479.513
• Mol file: 106115-82-6.mol

Synonyms:Benzyl-2-azido-3,4-di-O-<α,α-D2>benzyl-2-desoxy-β-D-glucopyranosid

Chemical Property of Benzyl-2-azido-3,4-di-O-<α,α-D2>benzyl-2-desoxy-β-D-glucopyranosid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzyl-2-azido-3,4-di-O-<α,α-D2>benzyl-2-desoxy-β-D-glucopyranosid

There total 3 articles about Benzyl-2-azido-3,4-di-O-<α,α-D2>benzyl-2-desoxy-β-D-glucopyranosid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Benzyl-6-O-acetyl-2-azido-3,4-di-O-<α,α-D2>benzyl-2-desoxy-β-D-glucopyranosid (106115-81-5) → Benzyl-2-azido-3,4-di-O-<α,α-D2>benzyl-2-desoxy-β-D-glucopyranosid (106115-82-6)

Guidance literature:

With sodium methylate; In methanol; dichloromethane; for 2h; Yield given;

Reference yield:

6-O-Acetyl-2-azido-3,4-di-O-<α,α-D2>benzyl-2-desoxy-α-D-glucopyranosylbromid (106139-07-5) → Benzyl-2-azido-3,4-di-O-<α,α-D2>benzyl-2-desoxy-β-D-glucopyranosid (106115-82-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / silver silicate, molecular sieve 4 Angstroem / CH₂Cl₂ / 2 h / -20 °C

2: 1 M NaOMe / CH₂Cl₂; methanol / 2 h

With silver silicate; 4 A molecular sieve; sodium methylate; In methanol; dichloromethane;

Reference yield:

1,6-Di-O-acetyl-2-azido-3,4-di-O-<α,α-D2>benzyl-2-desoxy-α,β-D-glucopyranose → Benzyl-2-azido-3,4-di-O-<α,α-D2>benzyl-2-desoxy-β-D-glucopyranosid (106115-82-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 98 percent / TiBr₄ / CH₂Cl₂; ethyl acetate / 12 h

2: 82 percent / silver silicate, molecular sieve 4 Angstroem / CH₂Cl₂ / 2 h / -20 °C

3: 1 M NaOMe / CH₂Cl₂; methanol / 2 h

With silver silicate; 4 A molecular sieve; sodium methylate; titanium(IV) bromide; In methanol; dichloromethane; ethyl acetate;

upstream raw materials:

Benzyl-6-O-acetyl-2-azido-3,4-di-O-<α,α-D2>benzyl-2-desoxy-β-D-glucopyranosid

6-O-Acetyl-2-azido-3,4-di-O-<α,α-D2>benzyl-2-desoxy-α-D-glucopyranosylbromid

Downstream raw materials:

Benzyl-2-azido-6-O-(2-azido-3-O-<α,α-D2>benzyl-2-desoxy-β-D-glucopyranosyl)-3,4-di-O-<α,α-D2>benzyl-2-desoxy-β-D-glucopyranosid

Benzyl-O--(2->6)-O-(2-amino-3-O-<α,α-D2>benzyl-2-desoxy-β-D-glucopyranosyl)-(1->6)-2-amino-3,4-di-O-<α,α-D2>benzyl-2-desoxy-β-D-glucopyranosid-dihydrochlorid

Benzyl-O--(2->6)-O-(2-azido-3-O-<α,α-D2>benzyl-2-desoxy-β-D-glucopyranosyl)-(1->6)-2-azido-3,4-di-O-<α,α-D2>benzyl-2-desoxy-β-D-glucopyranosid

Benzyl-6-O-<6-O-acetyl-2-amino-3-O-<α,α-D2>benzyl-2-desoxy-4-O-(diphenoxyphosphoryl)-β-D-glucopyranosyl>-2-amino-3,4-di-O-<α,α-D2>benzyl-2-desoxy-β-D-glucopyranosid-dihydrochlorid