Technology Process of 9,10-Dihydrobenz(e)acephenanthrylene-9,10-diol trans-
There total 10 articles about 9,10-Dihydrobenz(e)acephenanthrylene-9,10-diol trans- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium methylate;
In
tetrahydrofuran; methanol;
for 0.5h;
Ambient temperature;
DOI:10.1021/jo00325a028
- Guidance literature:
-
Multi-step reaction with 10 steps
1: 95 percent / H2 / 10percent Pd/C / ethyl acetate / 2 h / 1034.3 Torr
3: SOCl2 / benzene / 3 h / Heating
4: AlCl3 / CS2 / 1.) 0 deg C, 2.) reflux, 10 min
5: 88 percent / LiAlH4 / tetrahydrofuran / 0.33 h / 20 °C
6: 78 percent / conc. H2SO4 / acetic acid / 0.83 h / 70 °C
7: 65 percent / 1.) I2 / benzene / 1.) reflux, 2) reflux, 2.5 h
8: 48 percent / N-bromosuccinimide, α,α'-azobis(isobutyronitrile) / CCl4 / 2 h / Heating
9: 80 percent / 1,5-diazabicyclo<4.3.0>non-5-ene / tetrahydrofuran / 3 h / 0 °C
10: 36 percent / sodium methoxide / tetrahydrofuran; methanol / 0.5 h / Ambient temperature
With
N-Bromosuccinimide; lithium aluminium tetrahydride; aluminium trichloride; thionyl chloride; sulfuric acid; azobisisobutyronitrile; DBN; hydrogen; iodine; sodium methylate;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; carbon disulfide; tetrachloromethane; acetic acid; ethyl acetate; benzene;
DOI:10.1021/jo00325a028
- Guidance literature:
-
Multi-step reaction with 8 steps
1: SOCl2 / benzene / 3 h / Heating
2: AlCl3 / CS2 / 1.) 0 deg C, 2.) reflux, 10 min
3: 88 percent / LiAlH4 / tetrahydrofuran / 0.33 h / 20 °C
4: 78 percent / conc. H2SO4 / acetic acid / 0.83 h / 70 °C
5: 65 percent / 1.) I2 / benzene / 1.) reflux, 2) reflux, 2.5 h
6: 48 percent / N-bromosuccinimide, α,α'-azobis(isobutyronitrile) / CCl4 / 2 h / Heating
7: 80 percent / 1,5-diazabicyclo<4.3.0>non-5-ene / tetrahydrofuran / 3 h / 0 °C
8: 36 percent / sodium methoxide / tetrahydrofuran; methanol / 0.5 h / Ambient temperature
With
N-Bromosuccinimide; lithium aluminium tetrahydride; aluminium trichloride; thionyl chloride; sulfuric acid; azobisisobutyronitrile; DBN; iodine; sodium methylate;
In
tetrahydrofuran; methanol; carbon disulfide; tetrachloromethane; acetic acid; benzene;
DOI:10.1021/jo00325a028
