1-azabicyclo[2.2.2]oct-3-yl [2-(4‘-fluorobiphenyl-3-yl)propan-2-yl]carbamate

Base Information

Chemical Name:1-azabicyclo[2.2.2]oct-3-yl [2-(4‘-fluorobiphenyl-3-yl)propan-2-yl]carbamate
CAS No.:1401090-10-5
Molecular Formula:C₂₃H₂₇FN₂O₂
Molecular Weight:382.478
Hs Code.:

Synonyms:1-azabicyclo[2.2.2]oct-3-yl [2-(4‘-fluorobiphenyl-3-yl)propan-2-yl]carbamate

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Chemical Property of 1-azabicyclo[2.2.2]oct-3-yl [2-(4‘-fluorobiphenyl-3-yl)propan-2-yl]carbamate

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Technology Process of 1-azabicyclo[2.2.2]oct-3-yl [2-(4‘-fluorobiphenyl-3-yl)propan-2-yl]carbamate

There total 10 articles about 1-azabicyclo[2.2.2]oct-3-yl [2-(4‘-fluorobiphenyl-3-yl)propan-2-yl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 1401090-10-5
1-azabicyclo[2.2.2]oct-3-yl [2-(4‘-fluorobiphenyl-3-yl)propan-2-yl]carbamate

Guidance literature:: With palladium diacetate; sodium carbonate; In 1,2-dimethoxyethane; water; at 150 ℃; for 0.416667h; Microwave irradiation;

Reference yield: 44.0%

: 2-(4'-fluoro-[1,1'-biphenyl]-3-yl)propan-2-amine

: 123259-24-5
1-azabicyclo<2.2.2>oct-3-yl chloroformate hydrochloride

: 1401090-10-5
1-azabicyclo[2.2.2]oct-3-yl [2-(4‘-fluorobiphenyl-3-yl)propan-2-yl]carbamate

Guidance literature:: With pyridine; at 90 ℃; for 5h; Inert atmosphere;
DOI:10.1016/j.tetlet.2020.152352

Reference yield:

: 1765-93-1
4-fluoroboronic acid

: C₁₇H₂₃BrN₂O₂*(x)ClH

: 1401090-10-5
1-azabicyclo[2.2.2]oct-3-yl [2-(4‘-fluorobiphenyl-3-yl)propan-2-yl]carbamate

Guidance literature:: With palladium diacetate; sodium carbonate; In 1,2-dimethoxyethane; water; at 150 ℃; for 0.416667h; Reagent/catalyst; Solvent; Microwave irradiation;
DOI:10.1016/j.tetlet.2020.152352