7-cyclohexylthioethyl-6-methylamino-2-methyldithiocarbamylpurine

Base Information

• Chemical Name: 7-cyclohexylthioethyl-6-methylamino-2-methyldithiocarbamylpurine
• CAS No.: 108575-48-0
• Molecular Formula: C₁₆H₂₄N₆S₃
• Molecular Weight: 396.605
• Mol file: 108575-48-0.mol

Synonyms:7-cyclohexylthioethyl-6-methylamino-2-methyldithiocarbamylpurine

Chemical Property of 7-cyclohexylthioethyl-6-methylamino-2-methyldithiocarbamylpurine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 7-cyclohexylthioethyl-6-methylamino-2-methyldithiocarbamylpurine

There total 2 articles about 7-cyclohexylthioethyl-6-methylamino-2-methyldithiocarbamylpurine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

4-amino-1-cyclohexylthioethyl-5-cyanoimidazole (108555-74-4) + methyl thioisocyanate (556-61-6) → 7-cyclohexylthioethyl-6-methylamino-2-methyldithiocarbamylpurine (108575-48-0)

Guidance literature:

In pyridine; for 1h; Heating;

DOI:10.1002/jhet.5570230319

Reference yield:

1-[(2-chloroethyl)sulfanyl]cyclohexane (53787-05-6) → 7-cyclohexylthioethyl-6-methylamino-2-methyldithiocarbamylpurine (108575-48-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 24 percent / K₂CO₃ / tetrahydrofuran; dimethylformamide / 4 h / Heating

2: 41 percent / pyridine / 1 h / Heating

With potassium carbonate; In tetrahydrofuran; pyridine; N,N-dimethyl-formamide;

DOI:10.1002/jhet.5570230319

Reference yield: 98.0%

7-cyclohexylthioethyl-6-methylamino-2-methyldithiocarbamylpurine (108575-48-0) → 7-cyclohexylthioethyl-6-methylamino-2-thioxopurine (108575-49-1)

Guidance literature:

With hydrogenchloride; In methanol; for 0.75h; Heating;

DOI:10.1002/jhet.5570230319

upstream raw materials:

4-amino-1-cyclohexylthioethyl-5-cyanoimidazole

methyl thioisocyanate

1-[(2-chloroethyl)sulfanyl]cyclohexane

Downstream raw materials:

7-cyclohexylthioethyl-6-methylamino-2-thioxopurine