10,13-dimethyl-17-{1-methyl-4-[methyl(prop-2-ynyl)amino]-4-oxobutyl}-hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl 3,5-bis[(dimethoxyphosphoryl)methyl]benzoate

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Chemical Name:10,13-dimethyl-17-{1-methyl-4-[methyl(prop-2-ynyl)amino]-4-oxobutyl}-hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl 3,5-bis[(dimethoxyphosphoryl)methyl]benzoate
CAS No.:1061592-16-2
Molecular Formula:C₄₁H₆₃NO₉P₂
Molecular Weight:775.9
Hs Code.:

10,13-dimethyl-17-{1-methyl-4-[methyl(prop-2-ynyl)amino]-4-oxobutyl}-hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl 3,5-bis[(dimethoxyphosphoryl)methyl]benzoate

Synonyms:10,13-dimethyl-17-{1-methyl-4-[methyl(prop-2-ynyl)amino]-4-oxobutyl}-hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl 3,5-bis[(dimethoxyphosphoryl)methyl]benzoate

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Chemical Property of 10,13-dimethyl-17-{1-methyl-4-[methyl(prop-2-ynyl)amino]-4-oxobutyl}-hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl 3,5-bis[(dimethoxyphosphoryl)methyl]benzoate

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Technology Process of 10,13-dimethyl-17-{1-methyl-4-[methyl(prop-2-ynyl)amino]-4-oxobutyl}-hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl 3,5-bis[(dimethoxyphosphoryl)methyl]benzoate

There total 1 articles about 10,13-dimethyl-17-{1-methyl-4-[methyl(prop-2-ynyl)amino]-4-oxobutyl}-hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl 3,5-bis[(dimethoxyphosphoryl)methyl]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 1061592-08-2
4-(3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-N-methyl-N-(prop-2-ynyl)pentanamide

: 223449-19-2
5-carboxy-m-xylylenebisphosphonic acid tetramethyl ester

: 1061592-16-2
10,13-dimethyl-17-{1-methyl-4-[methyl(prop-2-ynyl)amino]-4-oxobutyl}-hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl 3,5-bis[(dimethoxyphosphoryl)methyl]benzoate

Guidance literature:: 5-carboxy-m-xylylenebisphosphonic acid tetramethyl ester; With 6-chloro-3-((dimethylamino)(dimethyliminio)methyl)-1H-benzo[d][1,2,3]triazol-3-ium-1-olatehexafluorophosphate(V); N-ethyl-N,N-diisopropylamine; 6-chloro-1-hydroxybenzotriazole; In dichloromethane; N,N-dimethyl-formamide; at 0 ℃; for 0.166667h;

4-(3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-N-methyl-N-(prop-2-ynyl)pentanamide; In dichloromethane; N,N-dimethyl-formamide; at 0 - 20 ℃; for 24h;
DOI:10.1055/s-2008-1067155