2-hydroxyoctyl benzoate

Base Information

• Chemical Name: 2-hydroxyoctyl benzoate
• CAS No.: 128733-31-3
• Molecular Formula: C₁₅H₂₂O₃
• Molecular Weight: 250.338
• Mol file: 128733-31-3.mol

Synonyms:2-hydroxyoctyl benzoate

Chemical Property of 2-hydroxyoctyl benzoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-hydroxyoctyl benzoate

There total 4 articles about 2-hydroxyoctyl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

benzoic acid (65-85-0,8013-63-6) + 1,2-Epoxyoctane (2984-50-1) → 2-hydroxyoctyl benzoate (128733-31-3)

Guidance literature:

With tetrabutylammomium bromide; In acetonitrile; for 5h; Heating;

DOI:10.1055/s-2003-42416

Reference yield:

1-(benzoyloxy)octan-2-one (80387-19-5) → 2-hydroxyoctyl benzoate (128733-31-3)

Guidance literature:

With dimethylsulfide borane complex; sodium sulfate; In decane; dimethyl sulfoxide; at 0 ℃;

DOI:10.1021/ol5027393

Reference yield:

oct-1-ene (111-66-0,25068-25-1) + benzoic acid (65-85-0,8013-63-6) → 2-hydroxyoctyl benzoate (128733-31-3)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine; tert.-butylhydroperoxide; iodine / dimethyl sulfoxide; decane / 12 h / 25 °C / Inert atmosphere

2: sodium sulfate; dimethylsulfide borane complex / dimethyl sulfoxide; decane / 0 °C

With tert.-butylhydroperoxide; dimethylsulfide borane complex; iodine; sodium sulfate; triethylamine; In decane; dimethyl sulfoxide;

DOI:10.1021/ol5027393

upstream raw materials:

1,2-octandiol

benzoyl chloride

benzoic acid

1,2-Epoxyoctane

Downstream raw materials:

1-(benzoyloxy)octan-2-one