4-(bromomethyl)-1-chloro-2-iodobenzene

Base Information

• Chemical Name: 4-(bromomethyl)-1-chloro-2-iodobenzene
• CAS No.: 136558-15-1
• Molecular Formula: C₇H₅BrClI
• Molecular Weight: 331.378
• Hs Code.: 2903998090

Synonyms:4-(bromomethyl)-1-chloro-2-iodobenzene

Chemical Property of 4-(bromomethyl)-1-chloro-2-iodobenzene

Chemical Property:

Purity/Quality:

4-(Bromomethyl)-1-chloro-2-iodo-Benzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(bromomethyl)-1-chloro-2-iodobenzene

There total 4 articles about 4-(bromomethyl)-1-chloro-2-iodobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

(4-chloro-3-iodo-phenyl)-methanol (104317-95-5) → 4-(bromomethyl)-1-chloro-2-iodobenzene (136558-15-1)

Guidance literature:

With carbon tetrabromide; triphenylphosphine; In dichloromethane; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1021/acs.jmedchem.1c00110

Reference yield:

4-chloro-3-iodobenzaldehyde (276866-90-1) → 4-(bromomethyl)-1-chloro-2-iodobenzene (136558-15-1)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium tetrahydroborate / methanol / 2 h / 20 °C / Inert atmosphere

2: carbon tetrabromide; triphenylphosphine / dichloromethane / 2 h / 20 °C / Inert atmosphere

With sodium tetrahydroborate; carbon tetrabromide; triphenylphosphine; In methanol; dichloromethane;

DOI:10.1021/acs.jmedchem.1c00110

Reference yield:

4-chlorobenzaldehyde (104-88-1) → 4-(bromomethyl)-1-chloro-2-iodobenzene (136558-15-1)

Guidance literature:

Multi-step reaction with 3 steps

1: iodine; sodium iodate; sulfuric acid / water / 1 h / 20 °C / Inert atmosphere

2: sodium tetrahydroborate / methanol / 2 h / 20 °C / Inert atmosphere

3: carbon tetrabromide; triphenylphosphine / dichloromethane / 2 h / 20 °C / Inert atmosphere

With sodium tetrahydroborate; sodium iodate; carbon tetrabromide; sulfuric acid; iodine; triphenylphosphine; In methanol; dichloromethane; water;

DOI:10.1021/acs.jmedchem.1c00110

upstream raw materials:

(4-chloro-3-iodo-phenyl)-methanol

4-chloro-3-iodobenzaldehyde

4-chlorobenzaldehyde

Downstream raw materials:

N-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-N-(3-iodo-4-chloro-benzyl)-4-methylbenzenesulfonamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 136558-15-1 4-(bromomethyl)-1-chloro-2-iodobenzene

Send

Send

Metric Ton KG G Pound L ML

Send

Send