phenyl (R)-4-ethyl-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole-4-carboxylate

Base Information

Chemical Name:phenyl (R)-4-ethyl-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole-4-carboxylate
CAS No.:1203507-12-3
Molecular Formula:C₁₉H₁₇NO₅
Molecular Weight:339.348
Hs Code.:

Synonyms:phenyl (R)-4-ethyl-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole-4-carboxylate

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Chemical Property of phenyl (R)-4-ethyl-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole-4-carboxylate

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Technology Process of phenyl (R)-4-ethyl-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole-4-carboxylate

There total 3 articles about phenyl (R)-4-ethyl-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1203507-11-2
4-ethyl-2-(4-methoxyphenyl)oxazol-5-yl phenyl carbonate

: 1203507-12-3
phenyl (R)-4-ethyl-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole-4-carboxylate

Guidance literature:: With (2S,3R)-3-isopropyl-2-phenyl-3,4-dihydro-2H-benzo[4,5]thiazolo[3,2-a]pyrimidine; In dichloromethane; at -50 ℃; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1002/anie.200904333

Reference yield:

: 1203507-11-2
4-ethyl-2-(4-methoxyphenyl)oxazol-5-yl phenyl carbonate

: 1203507-12-3
phenyl (R)-4-ethyl-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole-4-carboxylate

: 1316850-38-0
phenyl (S)-4-ethyl-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole-4-carboxylate

Guidance literature:: With (S)-5-benzyl-6,6-dimethyl-2-phenyl-5,6-dihydrooxazolo[2,3-c][1,2,4]triazol-2-ium tetrafluoroborate; potassium hexamethylsilazane; In toluene; at 20 ℃; optical yield given as %ee; enantioselective reaction;
DOI:10.1016/j.tetasy.2011.04.001

Reference yield:

: 1203507-11-2
4-ethyl-2-(4-methoxyphenyl)oxazol-5-yl phenyl carbonate

: 217446-34-9
4-ethyl-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole

: 1203507-12-3
phenyl (R)-4-ethyl-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole-4-carboxylate

: 1316850-38-0
phenyl (S)-4-ethyl-2-(4-methoxyphenyl)-5-oxo-4,5-dihydrooxazole-4-carboxylate

Guidance literature:: With (S)-5-benzyl-2-phenyl-6,8-dihydro-5H-[1,2,4]triazolo[3,4-c][1,4]oxazin-2-ium tetrafluoroborate; potassium hexamethylsilazane; In tetrahydrofuran; at 20 ℃; for 1h; optical yield given as %ee;
DOI:10.1016/j.tetasy.2011.04.001