alpha-(4-Chlorophenyl)-3-pyridazineethanethioamide

Base Information

Chemical Name:alpha-(4-Chlorophenyl)-3-pyridazineethanethioamide
CAS No.:81102-56-9
Molecular Formula:C₁₂H₁₀ClN₃S
Molecular Weight:263.75
Hs Code.:
DSSTox Substance ID:DTXSID101001777

Synonyms:BRN 5540603;alpha-(4-Chlorophenyl)-3-pyridazineethanethioamide;3-Pyridazineethanethioamide, alpha-(4-chlorophenyl)-;81102-56-9;DTXSID101001777;LS-129581;2-(4-Chlorophenyl)-2-(pyridazin-3-yl)ethanimidothioic acid

Suppliers and Price of alpha-(4-Chlorophenyl)-3-pyridazineethanethioamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of alpha-(4-Chlorophenyl)-3-pyridazineethanethioamide

Chemical Property:

Vapor Pressure:6.81E-10mmHg at 25°C
Boiling Point:493.8°C at 760 mmHg
Flash Point:252.4°C
Density:1.365g/cm³
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:263.0283962
Heavy Atom Count:17
Complexity:267

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=NN=C1)C(C2=CC=C(C=C2)Cl)C(=S)N

Technology Process of alpha-(4-Chlorophenyl)-3-pyridazineethanethioamide

There total 2 articles about alpha-(4-Chlorophenyl)-3-pyridazineethanethioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 140-53-4
p-chlorobenzyl cyanide

: 81102-56-9
2-(4-Chloro-phenyl)-2-pyridazin-3-yl-thioacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / sodium amide / benzene / 1.) 6 h, room temperature, 2.) 4 h, reflux

2: 1.) triethylamine, 2.) hydrogen sulfide / 1.) pyridine, 30 min, room temperature, 2.) pyridine, 20 min, 0 deg C, 2 days, room temperature

With hydrogen sulfide; sodium amide; triethylamine; In benzene;
DOI:10.1248/cpb.29.3433

Reference yield:

: 81102-50-3
(4-Chloro-phenyl)-pyridazin-3-yl-acetonitrile

: 81102-56-9
2-(4-Chloro-phenyl)-2-pyridazin-3-yl-thioacetamide

Guidance literature:: With hydrogen sulfide; triethylamine; Yield given. Multistep reaction; 1.) pyridine, 30 min, room temperature, 2.) pyridine, 20 min, 0 deg C, 2 days, room temperature;
DOI:10.1248/cpb.29.3433