Technology Process of 1-(bromomethyl)-3-(methyl-d3)benzene
There total 8 articles about 1-(bromomethyl)-3-(methyl-d3)benzene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
phosphorus tribromide;
In
diethyl ether; hexane;
at -20 - 20 ℃;
for 1.41667h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 33 percent / 1.) magnesium / 1.) ethyl ether, 0.5 h, 2.) reflux, 0.5 h
2: 75 percent / lithium tetrahydroaluminate / tetrahydrofuran
3: phosphorus tribromide / diethyl ether
With
lithium aluminium tetrahydride; phosphorus tribromide; magnesium;
In
tetrahydrofuran; diethyl ether;
DOI:10.1021/ja00411a007
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 92 percent / lithium tetradeuterioaluminate / tetrahydrofuran / 1.5 h
2: 91 percent / phosphorus tribromide / diethyl ether / 1.) 2h; 2.) reflux, 2 h
3: 64 percent / lithium tetradeuterioaluminate / tetrahydrofuran / 1.) 45 min, 2.) reflux, 3 h
4: 33 percent / 1.) magnesium / 1.) ethyl ether, 0.5 h, 2.) reflux, 0.5 h
5: 75 percent / lithium tetrahydroaluminate / tetrahydrofuran
6: phosphorus tribromide / diethyl ether
With
lithium aluminium tetrahydride; lithium aluminium deuteride; phosphorus tribromide; magnesium;
In
tetrahydrofuran; diethyl ether;
DOI:10.1021/ja00411a007
