methyl trans-4-((5-(6-((4-fluoro-3-methoxybenzyl)carbamoyl)-2-methyl-pyrimidin-4-yl)-2H-tetrazol-2-yl)methyl)cyclohexanecarboxylate

Base Information

Chemical Name:methyl trans-4-((5-(6-((4-fluoro-3-methoxybenzyl)carbamoyl)-2-methyl-pyrimidin-4-yl)-2H-tetrazol-2-yl)methyl)cyclohexanecarboxylate
CAS No.:1112168-71-4
Molecular Formula:C₂₄H₂₈FN₇O₄
Molecular Weight:497.529
Hs Code.:

Synonyms:methyl trans-4-((5-(6-((4-fluoro-3-methoxybenzyl)carbamoyl)-2-methyl-pyrimidin-4-yl)-2H-tetrazol-2-yl)methyl)cyclohexanecarboxylate

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Chemical Property of methyl trans-4-((5-(6-((4-fluoro-3-methoxybenzyl)carbamoyl)-2-methyl-pyrimidin-4-yl)-2H-tetrazol-2-yl)methyl)cyclohexanecarboxylate

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Technology Process of methyl trans-4-((5-(6-((4-fluoro-3-methoxybenzyl)carbamoyl)-2-methyl-pyrimidin-4-yl)-2H-tetrazol-2-yl)methyl)cyclohexanecarboxylate

There total 1 articles about methyl trans-4-((5-(6-((4-fluoro-3-methoxybenzyl)carbamoyl)-2-methyl-pyrimidin-4-yl)-2H-tetrazol-2-yl)methyl)cyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1112178-70-7
(1R,4R)-4-[(methylsulfonyloxy)methyl]cyclohexanecarboxylic acid methyl ester

: 1112178-24-1
N-(4-fluoro-3-methoxy-benzyl)-6-(2H-tetrazol-5-yl)pyrimidine-4-carboxamide

: 1112168-71-4
methyl trans-4-((5-(6-((4-fluoro-3-methoxybenzyl)carbamoyl)-2-methyl-pyrimidin-4-yl)-2H-tetrazol-2-yl)methyl)cyclohexanecarboxylate

Guidance literature:: With triethylamine; In N,N-dimethyl acetamide; at 80 - 90 ℃;

Reference yield:

: 1112168-71-4
methyl trans-4-((5-(6-((4-fluoro-3-methoxybenzyl)carbamoyl)-2-methyl-pyrimidin-4-yl)-2H-tetrazol-2-yl)methyl)cyclohexanecarboxylate

: 1112168-73-6
trans-4-((5-(6-((4-fluoro-3-methoxybenzyl)carbamoyl)-2-methyl-pyrimidin-4-yl)-2H-tetrazol-2-yl)methyl)cyclohexanecarboxylic acid

Guidance literature:: methyl trans-4-((5-(6-((4-fluoro-3-methoxybenzyl)carbamoyl)-2-methyl-pyrimidin-4-yl)-2H-tetrazol-2-yl)methyl)cyclohexanecarboxylate; With sodium hydroxide; water; In tetrahydrofuran; at 20 ℃;

With trifluoroacetic acid; In tetrahydrofuran; water;