Ioxotrizoic acid

Base Information

• Chemical Name: Ioxotrizoic acid
• CAS No.: 19863-06-0
• Molecular Formula: C₁₁H₉I₃N₂O₅
• Molecular Weight: 629.916
• Hs Code.: 2924299090
• Mol file: 19863-06-0.mol

Synonyms:Benzoicacid, 3-(acetylamino)-5-[(hydroxyacetyl)amino]-2,4,6-triiodo- (9CI); Benzoic acid,3-acetamido-5-glycolamido-2,4,6-triiodo- (6CI,8CI);3-Acetamido-5-(hydroxyacetamido)-2,4,6-triiodobenzoic acid; Ioxotrizoic acid

Chemical Property of Ioxotrizoic acid

Chemical Property:

• Vapor Pressure: 2.49E-18mmHg at 25°C
• Boiling Point: 660.2°Cat760mmHg
• Flash Point: 353.1°C
• PSA: 115.73000
• Density: 2.716g/cm³
• LogP: 2.23380

Purity/Quality:

99% ^*data from raw suppliers

IOXOTRIZOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Diagnostic aid (radiopaque medium) .

Technology Process of Ioxotrizoic acid

There total 6 articles about Ioxotrizoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(2-acetoxy-acetylamino)-5-acetylamino-2,4,6-triiodo-benzoic acid (19863-05-9) → 3-acetylamino-5-glycoloylamino-2,4,6-triiodo-benzoic acid (19863-06-0)

Guidance literature:

With sodium hydroxide;

DOI:10.1021/ja01594a066

Reference yield:

3-amino-5-nitro-benzoic acid (618-84-8) → 3-acetylamino-5-glycoloylamino-2,4,6-triiodo-benzoic acid (19863-06-0)

Guidance literature:

Multi-step reaction with 5 steps

2: Raney nickel; aqueous NH₃ / Hydrogenation

3: aqueous NaOH; aqueous KICl₂

4: concentrated H₂SO₄

5: aqueous NaOH

With ammonium hydroxide; sodium hydroxide; K⁽¹⁺⁾*Cl₂I^(1-); sulfuric acid; nickel;

DOI:10.1021/ja01594a066

Reference yield:

3-amino-5-glycoloylamino-benzoic acid (19714-81-9) → 3-acetylamino-5-glycoloylamino-2,4,6-triiodo-benzoic acid (19863-06-0)

Guidance literature:

Multi-step reaction with 3 steps

1: aqueous NaOH; aqueous KICl₂

2: concentrated H₂SO₄

3: aqueous NaOH

With sodium hydroxide; K⁽¹⁺⁾*Cl₂I^(1-); sulfuric acid;

DOI:10.1021/ja01594a066

upstream raw materials:

3-(2-acetoxy-acetylamino)-5-acetylamino-2,4,6-triiodo-benzoic acid

3-amino-5-nitro-benzoic acid

3-amino-5-glycoloylamino-benzoic acid

3-amino-5-glycoloylamino-2,4,6-triiodo-benzoic acid