1H-Indole-3-acetic acid, 2-methyl-, 2-(((4-chlorophenyl)amino)thioxomethyl)hydrazide

Base Information

Chemical Name:1H-Indole-3-acetic acid, 2-methyl-, 2-(((4-chlorophenyl)amino)thioxomethyl)hydrazide
CAS No.:54648-93-0
Molecular Formula:C18H17ClN4OS
Molecular Weight:372.8718
Hs Code.:
DSSTox Substance ID:DTXSID90203088

Synonyms:BRN 0450604;1H-Indole-3-acetic acid, 2-methyl-, 2-(((4-chlorophenyl)amino)thioxomethyl)hydrazide;2-Methyl-1H-indole-3-acetic acid 2-(((4-chlorophenyl)amino)thioxomethyl)hydrazide;5-22-03-00123 (Beilstein Handbook Reference);54648-93-0;C18H17ClN4OS;DTXSID90203088;C18-H17-Cl-N4-O-S;LS-82200

Suppliers and Price of 1H-Indole-3-acetic acid, 2-methyl-, 2-(((4-chlorophenyl)amino)thioxomethyl)hydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1H-Indole-3-acetic acid, 2-methyl-, 2-(((4-chlorophenyl)amino)thioxomethyl)hydrazide

Chemical Property:

Density:1.417g/cm³
XLogP3:3.8
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:372.0811600
Heavy Atom Count:25
Complexity:484

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C2=CC=CC=C2N1)CC(=O)NNC(=S)NC3=CC=C(C=C3)Cl

Technology Process of 1H-Indole-3-acetic acid, 2-methyl-, 2-(((4-chlorophenyl)amino)thioxomethyl)hydrazide

There total 5 articles about 1H-Indole-3-acetic acid, 2-methyl-, 2-(((4-chlorophenyl)amino)thioxomethyl)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 21909-51-3
2-(2-methyl-1H-indol-3-yl)acetohydrazide

: 2131-55-7
4-Chlorophenyl isothiocyanate

: 54648-93-0
1-(2-methylindolyl-3-acetyl)-4-p-chlorophenylthiosemicarbazide

Guidance literature:: In ethanol; for 1h; Heating;

Reference yield:

: 21909-49-9
ethyl (2-methylindol-3-yl)acetate

: 54648-93-0
1-(2-methylindolyl-3-acetyl)-4-p-chlorophenylthiosemicarbazide

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / N₂H₄*H₂O / ethanol / 10 h / Heating

2: 81 percent / ethanol / Heating

With hydrazine hydrate; In ethanol;

Reference yield:

: 59-88-1
phenylhydrazine hydrochloride

: 54648-93-0
1-(2-methylindolyl-3-acetyl)-4-p-chlorophenylthiosemicarbazide

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / conc. H₂SO₄

2: 65 percent / N₂H₄*H₂O / ethanol / 10 h / Heating

3: 81 percent / ethanol / Heating

With sulfuric acid; hydrazine hydrate; In ethanol;