O-(2,4,6-tri-O-benzoyl-3-O-benzyl-β-D-galactopyranosyl)-(1<*>3)-2,4,6-tri-O-benzoyl-α-D-galactopyranosyl chloride

Base Information

• Chemical Name: O-(2,4,6-tri-O-benzoyl-3-O-benzyl-β-D-galactopyranosyl)-(1<*>3)-2,4,6-tri-O-benzoyl-α-D-galactopyranosyl chloride
• CAS No.: 99605-97-7
• Molecular Formula: C₆₁H₅₁ClO₁₆
• Molecular Weight: 1075.52
• Mol file: 99605-97-7.mol

Synonyms:O-(2,4,6-tri-O-benzoyl-3-O-benzyl-β-D-galactopyranosyl)-(1<*>3)-2,4,6-tri-O-benzoyl-α-D-galactopyranosyl chloride

Chemical Property of O-(2,4,6-tri-O-benzoyl-3-O-benzyl-β-D-galactopyranosyl)-(1<*>3)-2,4,6-tri-O-benzoyl-α-D-galactopyranosyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O-(2,4,6-tri-O-benzoyl-3-O-benzyl-β-D-galactopyranosyl)-(1<*>3)-2,4,6-tri-O-benzoyl-α-D-galactopyranosyl chloride

There total 4 articles about O-(2,4,6-tri-O-benzoyl-3-O-benzyl-β-D-galactopyranosyl)-(1<*>3)-2,4,6-tri-O-benzoyl-α-D-galactopyranosyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.4%

O-(2,4,6-tri-O-benzoyl-3-O-benzyl-β-D-galactopyranosyl)-(1<*>3)-1-O-acetyl-2,4,6-tri-O-benzoyl-β-D-galactopyranose (99605-92-2) → O-(2,4,6-tri-O-benzoyl-3-O-benzyl-β-D-galactopyranosyl)-(1<*>3)-2,4,6-tri-O-benzoyl-α-D-galactopyranosyl chloride (99605-97-7)

Guidance literature:

With Dichloromethyl methyl ether; zinc(II) chloride; In chloroform; at 50 ℃; for 0.333333h;

DOI:10.1021/jo00225a063

Reference yield:

1-O-acetyl-2,4,6-tri-O-benzoyl-3-O-benzyl-β-D-galactopyranose (98056-59-8) → O-(2,4,6-tri-O-benzoyl-3-O-benzyl-β-D-galactopyranosyl)-(1<*>3)-2,4,6-tri-O-benzoyl-α-D-galactopyranosyl chloride (99605-97-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 90.7 percent / H₂ / 5percent Pd/C / 2-methoxy-ethanol; ethanol

2: 56 percent / silver triflate, sym-collidine / toluene; nitromethane / 1 h / -10 °C

3: 86.4 percent / 1,1-dichloromethyl methyl ether, ZnCl₂ / CHCl₃ / 0.33 h / 50 °C

With 2,4,6-trimethyl-pyridine; Dichloromethyl methyl ether; hydrogen; silver trifluoromethanesulfonate; zinc(II) chloride; palladium on activated charcoal; In nitromethane; ethanol; chloroform; 2-methoxy-ethanol; toluene;

DOI:10.1021/jo00225a063

Reference yield:

2,4,6-tri-O-benzoyl-3-O-benzyl-α-D-galactopyranosyl chloride (98056-58-7) → O-(2,4,6-tri-O-benzoyl-3-O-benzyl-β-D-galactopyranosyl)-(1<*>3)-2,4,6-tri-O-benzoyl-α-D-galactopyranosyl chloride (99605-97-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 56 percent / silver triflate, sym-collidine / toluene; nitromethane / 1 h / -10 °C

2: 86.4 percent / 1,1-dichloromethyl methyl ether, ZnCl₂ / CHCl₃ / 0.33 h / 50 °C

With 2,4,6-trimethyl-pyridine; Dichloromethyl methyl ether; silver trifluoromethanesulfonate; zinc(II) chloride; In nitromethane; chloroform; toluene;

DOI:10.1021/jo00225a063

upstream raw materials:

O-(2,4,6-tri-O-benzoyl-3-O-benzyl-β-D-galactopyranosyl)-(1<*>3)-1-O-acetyl-2,4,6-tri-O-benzoyl-β-D-galactopyranose

2,4,6-tri-O-benzoyl-3-O-benzyl-α-D-galactopyranosyl chloride

1-O-acetyl-2,4,6-tri-O-benzoyl-1β-D-galactopyranose

1-O-acetyl-2,4,6-tri-O-benzoyl-3-O-benzyl-β-D-galactopyranose