Technology Process of C36H35Cl4N5O10
There total 4 articles about C36H35Cl4N5O10 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / Inert atmosphere
2: toluene / 6.5 h / 20 - 80 °C / Inert atmosphere
With
thionyl chloride; N,N-dimethyl-formamide;
In
dichloromethane; toluene;
DOI:10.1021/ol300576n
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium carbonate / tetrahydrofuran; water / 20 °C / Inert atmosphere; Cooling with ice
2: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / Inert atmosphere
3: toluene / 6.5 h / 20 - 80 °C / Inert atmosphere
With
thionyl chloride; sodium carbonate; N,N-dimethyl-formamide;
In
tetrahydrofuran; dichloromethane; water; toluene;
DOI:10.1021/ol300576n
- Guidance literature:
-
Multi-step reaction with 4 steps
1: [bis(acetoxy)iodo]benzene / water; ethyl acetate; acetonitrile / 10 - 70 °C / Inert atmosphere
2: sodium carbonate / tetrahydrofuran; water / 20 °C / Inert atmosphere; Cooling with ice
3: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / Inert atmosphere
4: toluene / 6.5 h / 20 - 80 °C / Inert atmosphere
With
thionyl chloride; [bis(acetoxy)iodo]benzene; sodium carbonate; N,N-dimethyl-formamide;
In
tetrahydrofuran; dichloromethane; water; ethyl acetate; toluene; acetonitrile;
1: Hofmann rearrangement;
DOI:10.1021/ol300576n