Technology Process of C55H66N6O14
There total 12 articles about C55H66N6O14 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
bis(trichloromethyl) carbonate; C23H26N2O6;
With
triethylamine;
In
tetrahydrofuran;
at 0 ℃;
for 0.166667h;
Alloc-Phe-Lys(Boc)-PABOH;
With
triethylamine;
In
tetrahydrofuran;
at 20 - 65 ℃;
- Guidance literature:
-
C23H26N2O6;
With
bis(trichloromethyl) carbonate; triethylamine;
In
tetrahydrofuran;
at 0 ℃;
for 0.166667h;
Alloc-Phe-Lys(Boc)-PABOH;
With
triethylamine;
In
tetrahydrofuran;
at 20 - 65 ℃;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: trichloroisocyanuric acid; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / dichloromethane / 0 °C
2.1: 2,6-dimethylpyridine / dichloromethane / 1 h / -45 - 40 °C / Inert atmosphere
3.1: sodium carbonate / tetrakis(triphenylphosphine) palladium(0) / toluene; ethanol; water / Inert atmosphere
4.1: lithium borohydride; ethanol / tetrahydrofuran / 1 h / 15 - 25 °C / Cooling with ice
5.1: zinc; acetic acid / ethanol / 0.08 h / Reflux
6.1: triethylamine / tetrahydrofuran / 0.17 h / 0 °C
6.2: 20 - 65 °C
With
2,6-dimethylpyridine; lithium borohydride; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; ethanol; trichloroisocyanuric acid; sodium carbonate; acetic acid; triethylamine; zinc;
tetrakis(triphenylphosphine) palladium(0);
In
tetrahydrofuran; ethanol; dichloromethane; water; toluene;
3.1: Suzuki Coupling;
