Opiniazide

Base Information

• Chemical Name: Opiniazide
• CAS No.: 2779-55-7
• Molecular Formula: C₁₆H₁₅N₃O₅
• Molecular Weight: 329.312
• Hs Code.: 2933399090
• UNII: KD4681N5W4
• NCI Thesaurus Code: C90770
• ChEMBL ID: CHEMBL1403144
• Mol file: 2779-55-7.mol

Synonyms:1-(2-carboxy-3,4-dimethoxybenzylidene)-2-isonicotinoylhydrazone;opiniazide;saluzid

Chemical Property of Opiniazide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 110.11000
• Density: 1.31g/cm³
• LogP: 1.95180
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 6
• Exact Mass: 329.10117059
• Heavy Atom Count: 24
• Complexity: 465

Purity/Quality:

Saluzide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C(=C(C=C1)C=NNC(=O)C2=CC=NC=C2)C(=O)O)OC
• Isomeric SMILES: COC1=C(C(=C(C=C1)/C=N/NC(=O)C2=CC=NC=C2)C(=O)O)OC
• Uses: Saluzide is an anti-tuberculosis agent. Also, it is derived from Opianic Acid (O669300), which is a reagent used in the synthesis of novel 5-arylidene (thio)barbituric acid displaying urease activity.

Technology Process of Opiniazide

There total 1 articles about Opiniazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

isoniazid (54-85-3,7640-37-1) + opianic acid (519-05-1) → Saluzid (2779-55-7)

Guidance literature:

With water;

Reference yield:

Saluzid (2779-55-7) → 6-(isonicotinoylhydrazono-methyl)-2,3-dimethoxy-benzoic acid ethyl ester

Guidance literature:

With hydrogenchloride;

upstream raw materials:

isoniazid

opianic acid