Chlorpromazine sulfoxide

Base Information

Chemical Name:Chlorpromazine sulfoxide
CAS No.:969-99-3
Molecular Formula:C17H19 Cl N2 O S
Molecular Weight:334.87
Hs Code.:
NSC Number:170990
UNII:016U10PN9N
DSSTox Substance ID:DTXSID40871817
Nikkaji Number:J21.178H
Wikidata:Q27216080
ChEMBL ID:CHEMBL823
Mol file:969-99-3.mol

Synonyms:chlorpromazine sulfoxide;opromazine;opromazine hydrochloride

Suppliers and Price of Chlorpromazine sulfoxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
ChlorpromazineSulfoxide
250mg
$ 1210.00

TRC
ChlorpromazineSulfoxide
25mg
$ 155.00

Sigma-Aldrich
Chlorpromazine impurity A European Pharmacopoeia (EP) Reference Standard
y0000507
$ 190.00

Medical Isotopes, Inc.
ChlorpromazineSulfoxide
25 mg
$ 625.00

American Custom Chemicals Corporation
OXYCHLORPROMAZINE 95.00%
5MG
$ 504.00

Total 17 raw suppliers

Chemical Property of Chlorpromazine sulfoxide

Chemical Property:

Vapor Pressure:3.14E-10mmHg at 25°C
Melting Point:115°
Boiling Point:502.6°Cat760mmHg
PKA:pKa 9.0 (Uncertain)
Flash Point:257.8°C
PSA：42.76000
Density:1.35g/cm³
LogP:4.84060
Storage Temp.:Refrigerator, Under Inert Atmosphere
Solubility.:Chloroform (Sparingly), Methanol (Slightly)
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:334.0906621
Heavy Atom Count:22
Complexity:406

Purity/Quality:

97% ^*data from raw suppliers

ChlorpromazineSulfoxide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CCCN1C2=CC=CC=C2S(=O)C3=C1C=C(C=C3)Cl
Uses Chlorpromazine Sulfoxide is a derivative of Chlorpromazine Hydrochloride (C424750), which is a dopamine antagonist of the typical antipsychotic class of medications possessing additional antiadrenergic, antiserotonergic, anticholinergic and antihistaminergic properties used for schizophrenia treatment.

Technology Process of Chlorpromazine sulfoxide

There total 5 articles about Chlorpromazine sulfoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 50-53-3
2-chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine

: 1672-76-0
Chlorpromazine oxide

: 969-99-3
chlorpromazine sulfoxide

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; sodium hydroxide; In dichloromethane; at 0 ℃; for 4h;
DOI:10.1039/c3md00387f

Reference yield: 0.4%

: 50-53-3
2-chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine

: 2095-62-7
7-hydroxychlorpromazine

: 3926-66-7
2-chloro-10-(3-dimethylamino-propyl)-10H-phenothiazin-1-ol

: 3930-47-0
3-hydroxyl CPZ

: 969-99-3
chlorpromazine sulfoxide

Guidance literature:: 2-chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine; With ethylenediaminetetraacetic acid trisodium salt; oxygen; manganese (II) acetate tetrahydrate; ascorbic acid; In water; pH=4;

With ferrous(II) sulfate heptahydrate; ethylenediaminetetraacetic acid trisodium salt; oxygen; In water; at 45 ℃; for 2h;
DOI:10.1016/j.tetlet.2010.12.014