2-[2-propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5-(phenylmethoxy)phenoxy]propoxy]phenoxy]-benzoic acid methyl ester

Base Information

Chemical Name:2-[2-propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5-(phenylmethoxy)phenoxy]propoxy]phenoxy]-benzoic acid methyl ester
CAS No.:152609-83-1
Molecular Formula:C₄₁H₄₁FO₆
Molecular Weight:648.771
Hs Code.:

Synonyms:2-[2-propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5-(phenylmethoxy)phenoxy]propoxy]phenoxy]-benzoic acid methyl ester

Suppliers and Price of 2-[2-propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5-(phenylmethoxy)phenoxy]propoxy]phenoxy]-benzoic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[2-propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5-(phenylmethoxy)phenoxy]propoxy]phenoxy]-benzoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[2-propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5-(phenylmethoxy)phenoxy]propoxy]phenoxy]-benzoic acid methyl ester

There total 14 articles about 2-[2-propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5-(phenylmethoxy)phenoxy]propoxy]phenoxy]-benzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 152120-11-1
4-(benzyloxy)-5-(4-fluorophenyl)-2-(3-iodopropoxy)ethylbenzene

: 152609-76-2
2-(3-hydroxy-2-propylphenoxy)-benzoic acid methyl ester

: 152609-83-1
2-[2-propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5-(phenylmethoxy)phenoxy]propoxy]phenoxy]-benzoic acid methyl ester

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; for 24h; Ambient temperature;
DOI:10.1021/jm00022a006

Reference yield:

: 152120-07-5
2-benzyloxy-1-(4-fluorophenyl)-5-ethyl-4-(3-chloro-1-propyloxy)benzene

: 152609-76-2
2-(3-hydroxy-2-propylphenoxy)-benzoic acid methyl ester

: 152609-83-1
2-[2-propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5-(phenylmethoxy)phenoxy]propoxy]phenoxy]-benzoic acid methyl ester

Guidance literature:: With sodium iodide; potassium carbonate; In N-methyl-acetamide; butanone;

Reference yield:

: 151-10-0
1,3-Dimethoxybenzene

: 152609-83-1
2-[2-propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5-(phenylmethoxy)phenoxy]propoxy]phenoxy]-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) n-BuLi / 1.) THF, hexane, from -70 deg C to RT, 2.) THF, hexane, RT, 18 h, b) reflux, 5 h

2: 95 percent / Py*HCl / 8 h / 180 °C

3: 14 percent / copper bronze, K₂CO₃ / pyridine / 6 h / Heating

4: aq. NaOH / methanol / 48 h / Heating

5: conc. H₂SO₄ / 18 h / Heating

6: 78 percent / K₂CO₃ / dimethylformamide / 24 h / Ambient temperature

With sodium hydroxide; n-butyllithium; sulfuric acid; pyridine hydrochloride; copper; potassium carbonate; In pyridine; methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00022a006